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2jj9

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==CRYSTAL STRUCTURE OF MYOSIN-2 IN COMPLEX WITH ADP-METAVANADATE==
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<StructureSection load='2jj9' size='340' side='right' caption='[[2jj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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==Crystal structure of myosin-2 in complex with ADP-metavanadate==
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<StructureSection load='2jj9' size='340' side='right'caption='[[2jj9]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jj9]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJ9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JJ9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jj9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Dictyostelium_discoideum Dictyostelium discoideum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJ9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JJ9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1mne|1mne]], [[1d1c|1d1c]], [[1q5g|1q5g]], [[1jx2|1jx2]], [[1w9l|1w9l]], [[1mmn|1mmn]], [[1d0y|1d0y]], [[1vom|1vom]], [[2aka|2aka]], [[1lvk|1lvk]], [[1w9j|1w9j]], [[1jwy|1jwy]], [[1fmv|1fmv]], [[1yv3|1yv3]], [[1d0x|1d0x]], [[1fmw|1fmw]], [[1d1b|1d1b]], [[1mma|1mma]], [[1g8x|1g8x]], [[1d1a|1d1a]], [[1mmg|1mmg]], [[1w9i|1w9i]], [[1d0z|1d0z]], [[1w9k|1w9k]], [[1mnd|1mnd]], [[1mmd|1mmd]], [[2jhr|2jhr]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AD9:ADP+METAVANADATE'>AD9</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jj9 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2jj9 RCSB], [http://www.ebi.ac.uk/pdbsum/2jj9 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jj9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jj9 OCA], [https://pdbe.org/2jj9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jj9 RCSB], [https://www.ebi.ac.uk/pdbsum/2jj9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jj9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI]] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
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[https://www.uniprot.org/uniprot/MYS2_DICDI MYS2_DICDI] Myosin is a protein that binds to actin and has ATPase activity that is activated by actin.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jj9_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jj9_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jj9 ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2jj9" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Myosin|Myosin]]
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*[[Myosin 3D Structures|Myosin 3D Structures]]
== References ==
== References ==
<references/>
<references/>
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</StructureSection>
</StructureSection>
[[Category: Dictyostelium discoideum]]
[[Category: Dictyostelium discoideum]]
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[[Category: Baruch, P]]
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[[Category: Large Structures]]
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[[Category: Boehl, M]]
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[[Category: Baruch P]]
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[[Category: Brenner, B]]
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[[Category: Boehl M]]
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[[Category: Fedorov, R]]
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[[Category: Brenner B]]
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[[Category: Gutzeit, H O]]
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[[Category: Fedorov R]]
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[[Category: Hartmann, F K]]
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[[Category: Gutzeit HO]]
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[[Category: Knoelker, H J]]
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[[Category: Hartmann FK]]
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[[Category: Manstein, D J]]
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[[Category: Knoelker HJ]]
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[[Category: Martin, R]]
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[[Category: Manstein DJ]]
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[[Category: Tsiavaliaris, G]]
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[[Category: Martin R]]
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[[Category: Actin-binding]]
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[[Category: Tsiavaliaris G]]
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[[Category: Atp-analog]]
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[[Category: Atp-binding]]
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[[Category: Calmodulin-binding]]
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[[Category: Contractile protein]]
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[[Category: Methylation]]
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[[Category: Motor protein]]
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[[Category: Motor-domain]]
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[[Category: Myosin]]
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[[Category: Nucleotide-binding]]
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[[Category: Phosphoprotein]]
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Current revision

Crystal structure of myosin-2 in complex with ADP-metavanadate

PDB ID 2jj9

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