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2jjv

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==STRUCTURE OF HUMAN SIGNAL REGULATORY PROTEIN (SIRP) BETA(2)==
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<StructureSection load='2jjv' size='340' side='right' caption='[[2jjv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
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==Structure of human signal regulatory protein (sirp) beta(2)==
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<StructureSection load='2jjv' size='340' side='right'caption='[[2jjv]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2jjv]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJV OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2JJV FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2jjv]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JJV OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JJV FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2jju|2jju]], [[2jjw|2jjw]], [[2uv3|2uv3]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjv OCA], [http://pdbe.org/2jjv PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2jjv RCSB], [http://www.ebi.ac.uk/pdbsum/2jjv PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jjv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jjv OCA], [https://pdbe.org/2jjv PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jjv RCSB], [https://www.ebi.ac.uk/pdbsum/2jjv PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jjv ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/SIRBL_HUMAN SIRBL_HUMAN]] Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes (By similarity).
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[https://www.uniprot.org/uniprot/SIRBL_HUMAN SIRBL_HUMAN] Immunoglobulin-like cell surface receptor involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjv_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jj/2jjv_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jjv ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: Barclay, A N]]
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[[Category: Large Structures]]
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[[Category: Graham, S C]]
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[[Category: Barclay AN]]
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[[Category: Harlos, K]]
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[[Category: Graham SC]]
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[[Category: Hatherley, D]]
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[[Category: Harlos K]]
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[[Category: Stuart, D I]]
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[[Category: Hatherley D]]
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[[Category: Turner, J]]
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[[Category: Stuart DI]]
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[[Category: Immune system]]
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[[Category: Turner J]]
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[[Category: Immunoglobulin superfamily]]
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[[Category: Paired receptor]]
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[[Category: Signal regulatory protein beta]]
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[[Category: Sirp]]
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[[Category: Sirpb2]]
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Current revision

Structure of human signal regulatory protein (sirp) beta(2)

PDB ID 2jjv

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