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2uwx

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==Active site restructuring regulates ligand recognition in class A penicillin-binding proteins==
==Active site restructuring regulates ligand recognition in class A penicillin-binding proteins==
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<StructureSection load='2uwx' size='340' side='right' caption='[[2uwx]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
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<StructureSection load='2uwx' size='340' side='right'caption='[[2uwx]], [[Resolution|resolution]] 2.39&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uwx]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Strr6 Strr6]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bg3 2bg3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UWX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2uwx]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2bg3 2bg3]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UWX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UWX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.39&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=NC1:NITROCEFIN+ACYL-SERINE'>NC1</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NC1:NITROCEFIN+ACYL-SERINE'>NC1</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2uwy|2uwy]]</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwx OCA], [https://pdbe.org/2uwx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uwx RCSB], [https://www.ebi.ac.uk/pdbsum/2uwx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uwx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uwx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uwx OCA], [http://pdbe.org/2uwx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uwx RCSB], [http://www.ebi.ac.uk/pdbsum/2uwx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2uwx ProSAT]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7CRA4_STRR6 Q7CRA4_STRR6]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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==See Also==
==See Also==
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*[[Penicillin-binding protein|Penicillin-binding protein]]
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*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Strr6]]
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[[Category: Large Structures]]
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[[Category: Dessen, A]]
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[[Category: Streptococcus pneumoniae R6]]
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[[Category: DiGuilmi, A M]]
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[[Category: Dessen A]]
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[[Category: Dideberg, O]]
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[[Category: DiGuilmi AM]]
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[[Category: Job, V]]
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[[Category: Dideberg O]]
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[[Category: Macheboeuf, P]]
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[[Category: Job V]]
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[[Category: Vernet, T]]
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[[Category: Macheboeuf P]]
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[[Category: Acyltransferase]]
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[[Category: Vernet T]]
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[[Category: Cell wall]]
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[[Category: Glycosyltransferase]]
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[[Category: Peptidoglycan]]
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[[Category: Peptidoglycan synthesis multifunctional enzyme]]
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[[Category: Transferase]]
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Current revision

Active site restructuring regulates ligand recognition in class A penicillin-binding proteins

PDB ID 2uwx

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