2uxs
From Proteopedia
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| - | [[Image:2uxs.png|left|200px]] | ||
| - | + | ==2.7A crystal structure of inorganic pyrophosphatase (Rv3628) from Mycobacterium tuberculosis at pH 7.5== | |
| - | + | <StructureSection load='2uxs' size='340' side='right'caption='[[2uxs]], [[Resolution|resolution]] 2.70Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[2uxs]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Mycobacterium_tuberculosis_H37Rv Mycobacterium tuberculosis H37Rv]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UXS OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UXS FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7Å</td></tr> | |
| - | == | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr> |
| - | [[2uxs]] is a 3 chain structure | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uxs FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uxs OCA], [https://pdbe.org/2uxs PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uxs RCSB], [https://www.ebi.ac.uk/pdbsum/2uxs PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uxs ProSAT], [https://www.topsan.org/Proteins/RSGI/2uxs TOPSAN]</span></td></tr> |
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/IPYR_MYCTU IPYR_MYCTU] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/ux/2uxs_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2uxs ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
| - | *[[Inorganic pyrophosphatase|Inorganic pyrophosphatase]] | + | *[[Inorganic pyrophosphatase 3D structures|Inorganic pyrophosphatase 3D structures]] |
| - | [[Category: | + | __TOC__ |
| - | [[Category: Mycobacterium tuberculosis]] | + | </StructureSection> |
| - | [[Category: Cianci | + | [[Category: Large Structures]] |
| - | [[Category: Cole | + | [[Category: Mycobacterium tuberculosis H37Rv]] |
| - | [[Category: Hall | + | [[Category: Cianci M]] |
| - | [[Category: Hasnain | + | [[Category: Cole RE]] |
| - | [[Category: Kigawa | + | [[Category: Hall JF]] |
| - | [[Category: Matsuda | + | [[Category: Hasnain SS]] |
| - | [[Category: Tabernero | + | [[Category: Kigawa T]] |
| - | [[Category: Yokoyama | + | [[Category: Matsuda T]] |
| - | + | [[Category: Tabernero L]] | |
| - | + | [[Category: Yokoyama S]] | |
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Current revision
2.7A crystal structure of inorganic pyrophosphatase (Rv3628) from Mycobacterium tuberculosis at pH 7.5
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