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2uy7

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==CRYSTAL STRUCTURE OF THE P PILUS ROD SUBUNIT PAPA==
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<StructureSection load='2uy7' size='340' side='right' caption='[[2uy7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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==Crystal structure of the P pilus rod subunit PapA==
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<StructureSection load='2uy7' size='340' side='right'caption='[[2uy7]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2uy7]] is a 8 chain structure with sequence from [http://en.wikipedia.org/wiki/"bacillus_coli"_migula_1895 "bacillus coli" migula 1895] and [http://en.wikipedia.org/wiki/Ecout Ecout]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UY7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2UY7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2uy7]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli] and [https://en.wikipedia.org/wiki/Escherichia_coli_UTI89 Escherichia coli UTI89]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2UY7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2UY7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2uy6|2uy6]], [[1n0l|1n0l]], [[1pdk|1pdk]], [[1qpp|1qpp]], [[1qpx|1qpx]], [[2j2z|2j2z]], [[2j7l|2j7l]], [[3dpa|3dpa]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2uy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uy7 OCA], [http://pdbe.org/2uy7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2uy7 RCSB], [http://www.ebi.ac.uk/pdbsum/2uy7 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2uy7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2uy7 OCA], [https://pdbe.org/2uy7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2uy7 RCSB], [https://www.ebi.ac.uk/pdbsum/2uy7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2uy7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/PAPA_ECOLX PAPA_ECOLX]] Polymerizes to form the thick (6.8 nm in diameter) rod of the pilus (also called fimbria). The rod is a right-handed helical cylinder with 3.28 PapA subunits per turn. Pili are polar filaments radiating from the surface of the bacterium to a length of 0.5-1.5 micrometers and numbering 100-300 per cell, and enable bacteria to colonize the epithelium of specific host organs.
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[https://www.uniprot.org/uniprot/Q1R2W9_ECOUT Q1R2W9_ECOUT]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uy7_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/uy/2uy7_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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==See Also==
==See Also==
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*[[Pilin|Pilin]]
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*[[Pilin 3D structures|Pilin 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus coli migula 1895]]
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[[Category: Escherichia coli]]
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[[Category: Ecout]]
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[[Category: Escherichia coli UTI89]]
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[[Category: Bullitt, E]]
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[[Category: Large Structures]]
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[[Category: Hultgren, S J]]
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[[Category: Bullitt E]]
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[[Category: Verger, D]]
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[[Category: Hultgren SJ]]
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[[Category: Waksman, G]]
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[[Category: Verger D]]
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[[Category: Chaperone]]
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[[Category: Waksman G]]
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[[Category: Donor strand complementation]]
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[[Category: Donor-strand exchange]]
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[[Category: Dsc]]
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[[Category: Dse]]
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[[Category: Fimbria]]
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[[Category: Nte]]
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[[Category: Papa]]
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[[Category: Papd]]
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[[Category: Pili/n-terminal extension]]
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[[Category: Pilus biogenesis]]
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Current revision

Crystal structure of the P pilus rod subunit PapA

PDB ID 2uy7

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