This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2v3r

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:04, 13 December 2023) (edit) (undo)
 
(3 intermediate revisions not shown.)
Line 1: Line 1:
==Hypocrea jecorina Cel7A in complex with (S)-dihydroxy-phenanthrenolol==
==Hypocrea jecorina Cel7A in complex with (S)-dihydroxy-phenanthrenolol==
-
<StructureSection load='2v3r' size='340' side='right' caption='[[2v3r]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
+
<StructureSection load='2v3r' size='340' side='right'caption='[[2v3r]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2v3r]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Hypocrea_jecorina Hypocrea jecorina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V3R OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V3R FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2v3r]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trichoderma_reesei Trichoderma reesei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V3R OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V3R FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=XX7:2-{[(2S)-2-HYDROXY-3-(9-PHENANTHRYLOXY)PROPYL]AMINO}PROPANE-1,3-DIOL'>XX7</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CO:COBALT+(II)+ION'>CO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=PCA:PYROGLUTAMIC+ACID'>PCA</scene>, <scene name='pdbligand=XX7:2-{[(2S)-2-HYDROXY-3-(9-PHENANTHRYLOXY)PROPYL]AMINO}PROPANE-1,3-DIOL'>XX7</scene></td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1az6|1az6]], [[1azh|1azh]], [[1azj|1azj]], [[1azk|1azk]], [[1cbh|1cbh]], [[1cel|1cel]], [[1dy4|1dy4]], [[1egn|1egn]], [[1q2b|1q2b]], [[1q2e|1q2e]], [[2cbh|2cbh]], [[2cel|2cel]], [[2jf8|2jf8]], [[2v3i|2v3i]], [[3cel|3cel]], [[4cel|4cel]], [[5cel|5cel]], [[6cel|6cel]], [[7cel|7cel]], [[8cel|8cel]]</td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v3r OCA], [https://pdbe.org/2v3r PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v3r RCSB], [https://www.ebi.ac.uk/pdbsum/2v3r PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v3r ProSAT]</span></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Cellulose_1,4-beta-cellobiosidase_(non-reducing_end) Cellulose 1,4-beta-cellobiosidase (non-reducing end)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.91 3.2.1.91] </span></td></tr>
+
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v3r FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v3r OCA], [http://pdbe.org/2v3r PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v3r RCSB], [http://www.ebi.ac.uk/pdbsum/2v3r PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v3r ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE]] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
+
[https://www.uniprot.org/uniprot/GUX1_HYPJE GUX1_HYPJE] The biological conversion of cellulose to glucose generally requires three types of hydrolytic enzymes: (1) Endoglucanases which cut internal beta-1,4-glucosidic bonds; (2) Exocellobiohydrolases that cut the dissaccharide cellobiose from the non-reducing end of the cellulose polymer chain; (3) Beta-1,4-glucosidases which hydrolyze the cellobiose and other short cello-oligosaccharides to glucose.
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 22: Line 20:
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v3r ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v3r ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
 +
 +
==See Also==
 +
*[[Cellobiohydrolase 3D structures|Cellobiohydrolase 3D structures]]
 +
*[[Glucanase 3D structures|Glucanase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Hypocrea jecorina]]
+
[[Category: Large Structures]]
-
[[Category: Berg, U]]
+
[[Category: Trichoderma reesei]]
-
[[Category: Fagerstrom, A]]
+
[[Category: Berg U]]
-
[[Category: Sandgren, M]]
+
[[Category: Fagerstrom A]]
-
[[Category: Stahlberg, J]]
+
[[Category: Sandgren M]]
-
[[Category: Carbohydrate metabolism]]
+
[[Category: Stahlberg J]]
-
[[Category: Cellulose deagradation]]
+
-
[[Category: Cellulose degradation]]
+
-
[[Category: Chiral separation]]
+
-
[[Category: Glycoprotein]]
+
-
[[Category: Glycosidase]]
+
-
[[Category: Hydrolase]]
+
-
[[Category: Polysaccharide degradation]]
+
-
[[Category: Pyrrolidone carboxylic acid]]
+

Current revision

Hypocrea jecorina Cel7A in complex with (S)-dihydroxy-phenanthrenolol

PDB ID 2v3r

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools