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2v6o

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==Structure of Schistosoma mansoni Thioredoxin-Glutathione Reductase (SmTGR)==
==Structure of Schistosoma mansoni Thioredoxin-Glutathione Reductase (SmTGR)==
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<StructureSection load='2v6o' size='340' side='right' caption='[[2v6o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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<StructureSection load='2v6o' size='340' side='right'caption='[[2v6o]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2v6o]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Blood_fluke Blood fluke]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V6O OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2V6O FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2v6o]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Schistosoma_mansoni Schistosoma mansoni]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V6O OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V6O FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Thioredoxin-disulfide_reductase Thioredoxin-disulfide reductase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.8.1.9 1.8.1.9] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=FAD:FLAVIN-ADENINE+DINUCLEOTIDE'>FAD</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene>, <scene name='pdbligand=PG4:TETRAETHYLENE+GLYCOL'>PG4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2v6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v6o OCA], [http://pdbe.org/2v6o PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2v6o RCSB], [http://www.ebi.ac.uk/pdbsum/2v6o PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2v6o ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v6o FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v6o OCA], [https://pdbe.org/2v6o PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v6o RCSB], [https://www.ebi.ac.uk/pdbsum/2v6o PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v6o ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q962Y6_SCHMA Q962Y6_SCHMA]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Blood fluke]]
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[[Category: Large Structures]]
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[[Category: Thioredoxin-disulfide reductase]]
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[[Category: Schistosoma mansoni]]
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[[Category: Angelucci, F]]
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[[Category: Angelucci F]]
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[[Category: Bellelli, A]]
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[[Category: Bellelli A]]
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[[Category: Boumis, G]]
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[[Category: Boumis G]]
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[[Category: Brunori, M]]
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[[Category: Brunori M]]
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[[Category: Dimastrogiovanni, D]]
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[[Category: Dimastrogiovanni D]]
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[[Category: Miele, A E]]
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[[Category: Miele AE]]
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[[Category: Chimeric enzyme]]
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[[Category: Fad]]
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[[Category: Flavoprotein]]
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[[Category: Oxidoreductase]]
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[[Category: Redox-active center]]
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[[Category: Thiol-mediated detoxification pathway]]
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Current revision

Structure of Schistosoma mansoni Thioredoxin-Glutathione Reductase (SmTGR)

PDB ID 2v6o

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