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2v8z

From Proteopedia

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[[Image:2v8z.png|left|200px]]
 
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==Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12==
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The line below this paragraph, containing "STRUCTURE_2v8z", creates the "Structure Box" on the page.
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<StructureSection load='2v8z' size='340' side='right'caption='[[2v8z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2v8z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8Z FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8z OCA], [https://pdbe.org/2v8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8z RCSB], [https://www.ebi.ac.uk/pdbsum/2v8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8z ProSAT]</span></td></tr>
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{{STRUCTURE_2v8z| PDB=2v8z | SCENE= }}
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin.
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8z_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v8z ConSurf].
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<div style="clear:both"></div>
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===CRYSTAL STRUCTURE OF YAGE, A PROPHAGE PROTEIN BELONGING TO THE DIHYDRODIPICOLINIC ACID SYNTHASE FAMILY FROM E. COLI K12===
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==See Also==
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*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]]
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2v8z]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA].
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[[Category: Escherichia coli K-12]]
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[[Category: Large Structures]]
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==Reference==
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[[Category: Albeck S]]
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<ref group="xtra">PMID:018361457</ref><references group="xtra"/>
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[[Category: Bourenkov G]]
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[[Category: Escherichia coli]]
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[[Category: Dym O]]
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[[Category: Albeck, S.]]
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[[Category: Greenblatt HM]]
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[[Category: Bourenkov, G.]]
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[[Category: Krishnaswamy S]]
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[[Category: Dym, O.]]
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[[Category: Lamzin V]]
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[[Category: Greenblatt, H M.]]
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[[Category: Manicka S]]
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[[Category: Krishnaswamy, S.]]
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[[Category: Peleg Y]]
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[[Category: Lamzin, V.]]
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[[Category: Sussman JL]]
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[[Category: Manicka, S.]]
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[[Category: Unger T]]
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[[Category: Peleg, Y.]]
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[[Category: Sussman, J L.]]
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[[Category: Unger, T.]]
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[[Category: Dhdp]]
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[[Category: Lyase]]
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[[Category: N-acetyl neuraminate lyase]]
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[[Category: Nal]]
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Current revision

Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12

PDB ID 2v8z

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