2v8z
From Proteopedia
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- | [[Image:2v8z.png|left|200px]] | ||
- | + | ==Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12== | |
- | + | <StructureSection load='2v8z' size='340' side='right'caption='[[2v8z]], [[Resolution|resolution]] 2.20Å' scene=''> | |
- | + | == Structural highlights == | |
- | + | <table><tr><td colspan='2'>[[2v8z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2V8Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2V8Z FirstGlance]. <br> | |
- | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> | |
- | == | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2v8z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2v8z OCA], [https://pdbe.org/2v8z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2v8z RCSB], [https://www.ebi.ac.uk/pdbsum/2v8z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2v8z ProSAT]</span></td></tr> |
- | [[2v8z]] is a 4 chain structure with sequence from [ | + | </table> |
+ | == Function == | ||
+ | [https://www.uniprot.org/uniprot/YAGE_ECOLI YAGE_ECOLI] Catalyzes the formation of 2-keto-3-deoxy-galactonate (KDGal) from pyruvate and glyceraldehyde. Overexpression leads to increased growth (over 2 hours) in the presence of the antibiotics norfloxacin, ampicillin and streptomycin. | ||
+ | == Evolutionary Conservation == | ||
+ | [[Image:Consurf_key_small.gif|200px|right]] | ||
+ | Check<jmol> | ||
+ | <jmolCheckbox> | ||
+ | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/v8/2v8z_consurf.spt"</scriptWhenChecked> | ||
+ | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
+ | <text>to colour the structure by Evolutionary Conservation</text> | ||
+ | </jmolCheckbox> | ||
+ | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2v8z ConSurf]. | ||
+ | <div style="clear:both"></div> | ||
==See Also== | ==See Also== | ||
*[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]] | *[[Dihydrodipicolinate synthase|Dihydrodipicolinate synthase]] | ||
- | + | __TOC__ | |
- | + | </StructureSection> | |
- | + | [[Category: Escherichia coli K-12]] | |
- | [[Category: Escherichia coli]] | + | [[Category: Large Structures]] |
- | [[Category: Albeck | + | [[Category: Albeck S]] |
- | [[Category: Bourenkov | + | [[Category: Bourenkov G]] |
- | [[Category: Dym | + | [[Category: Dym O]] |
- | [[Category: Greenblatt | + | [[Category: Greenblatt HM]] |
- | [[Category: Krishnaswamy | + | [[Category: Krishnaswamy S]] |
- | [[Category: Lamzin | + | [[Category: Lamzin V]] |
- | [[Category: Manicka | + | [[Category: Manicka S]] |
- | [[Category: Peleg | + | [[Category: Peleg Y]] |
- | [[Category: Sussman | + | [[Category: Sussman JL]] |
- | [[Category: Unger | + | [[Category: Unger T]] |
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Current revision
Crystal Structure of YagE, a prophage protein belonging to the dihydrodipicolinic acid synthase family from E. coli K12
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Categories: Escherichia coli K-12 | Large Structures | Albeck S | Bourenkov G | Dym O | Greenblatt HM | Krishnaswamy S | Lamzin V | Manicka S | Peleg Y | Sussman JL | Unger T