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2vvt

From Proteopedia

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Current revision (15:34, 13 December 2023) (edit) (undo)
 
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<StructureSection load='2vvt' size='340' side='right'caption='[[2vvt]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
<StructureSection load='2vvt' size='340' side='right'caption='[[2vvt]], [[Resolution|resolution]] 1.65&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2vvt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"enterococcus_proteiformis"_thiercelin_and_jouhaud_1903 "enterococcus proteiformis" thiercelin and jouhaud 1903]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VVT FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2vvt]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Enterococcus_faecalis Enterococcus faecalis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2VVT OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2VVT FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=I24:2-BUTOXY-9-(2,6-DIFLUOROBENZYL)-N-(2-MORPHOLIN-4-YLETHYL)-9H-PURIN-6-AMINE'>I24</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.65&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2jfp|2jfp]], [[2jfo|2jfo]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DGL:D-GLUTAMIC+ACID'>DGL</scene>, <scene name='pdbligand=I24:2-BUTOXY-9-(2,6-DIFLUOROBENZYL)-N-(2-MORPHOLIN-4-YLETHYL)-9H-PURIN-6-AMINE'>I24</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Glutamate_racemase Glutamate racemase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.1.1.3 5.1.1.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvt OCA], [https://pdbe.org/2vvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vvt RCSB], [https://www.ebi.ac.uk/pdbsum/2vvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvt ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2vvt FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2vvt OCA], [https://pdbe.org/2vvt PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2vvt RCSB], [https://www.ebi.ac.uk/pdbsum/2vvt PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2vvt ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/MURI_ENTFA MURI_ENTFA] Provides the (R)-glutamate required for cell wall biosynthesis.[HAMAP-Rule:MF_00258]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Enterococcus proteiformis thiercelin and jouhaud 1903]]
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[[Category: Enterococcus faecalis]]
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[[Category: Glutamate racemase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Breault, G]]
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[[Category: Breault G]]
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[[Category: Comita-Prevoir, J]]
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[[Category: Comita-Prevoir J]]
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[[Category: Doig, P]]
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[[Category: Doig P]]
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[[Category: Eyermann, C]]
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[[Category: Eyermann C]]
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[[Category: Geng, B]]
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[[Category: Geng B]]
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[[Category: Gorseth, E]]
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[[Category: Gorseth E]]
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[[Category: Lundqvist, T]]
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[[Category: Lundqvist T]]
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[[Category: Noonan, B]]
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[[Category: Noonan B]]
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[[Category: Petrichko, R]]
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[[Category: Petrichko R]]
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[[Category: Benzyl purine]]
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[[Category: Cell shape]]
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[[Category: Cell wall biogenesis/degradation]]
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[[Category: Isomerase]]
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[[Category: Muri inhibitor]]
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[[Category: Peptidoglycan synthesis]]
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Current revision

Glutamate Racemase (MurI) from E. faecalis in complex with a 9-Benzyl Purine inhibitor

PDB ID 2vvt

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Proteopedia Page Contributors and Editors (what is this?)

OCA

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