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2w4m

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[[Image:2w4m.png|left|200px]]
 
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{{STRUCTURE_2w4m| PDB=2w4m | SCENE= }}
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==The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP==
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<StructureSection load='2w4m' size='340' side='right'caption='[[2w4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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===THE CRYSTAL STRUCTURE OF HUMAN N-ACETYLNEURAMINIC ACID PHOSPHATASE, NANP===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2w4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4M FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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[[2w4m]] is a 1 chain structure of [[Acid phosphatase]] with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4m OCA], [https://pdbe.org/2w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4m RCSB], [https://www.ebi.ac.uk/pdbsum/2w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4m ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NANP_HUMAN NANP_HUMAN]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w4/2w4m_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w4m ConSurf].
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<div style="clear:both"></div>
==See Also==
==See Also==
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*[[Acid phosphatase|Acid phosphatase]]
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*[[Acid phosphatase 3D structures|Acid phosphatase 3D structures]]
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: N-acylneuraminate-9-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H.]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C.]]
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[[Category: Bountra C]]
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[[Category: Cocking, R.]]
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[[Category: Cocking R]]
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[[Category: Delft, F Von.]]
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[[Category: Edwards A]]
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[[Category: Edwards, A.]]
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[[Category: Muniz JRC]]
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[[Category: Muniz, J R.C.]]
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[[Category: Oppermann U]]
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[[Category: Oppermann, U.]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W.]]
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[[Category: Roos A]]
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[[Category: Roos, A.]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E.]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J.]]
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[[Category: Yue WW]]
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[[Category: Yue, W W.]]
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[[Category: Von Delft F]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Hdhd4]]
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[[Category: Hydrolase]]
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[[Category: Magnesium]]
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[[Category: N-acetylneuraminate]]
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[[Category: N-acetylneuraminic acid phosphatase]]
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[[Category: Nanp]]
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[[Category: Neu5ac-9- phosphate]]
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[[Category: Sialic acid]]
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Current revision

The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP

PDB ID 2w4m

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