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2w4m

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==The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP==
==The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP==
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<StructureSection load='2w4m' size='340' side='right' caption='[[2w4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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<StructureSection load='2w4m' size='340' side='right'caption='[[2w4m]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2w4m]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W4M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2w4m]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W4M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W4M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/N-acylneuraminate-9-phosphatase N-acylneuraminate-9-phosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.3.29 3.1.3.29] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4m OCA], [http://pdbe.org/2w4m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w4m RCSB], [http://www.ebi.ac.uk/pdbsum/2w4m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w4m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w4m OCA], [https://pdbe.org/2w4m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w4m RCSB], [https://www.ebi.ac.uk/pdbsum/2w4m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w4m ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/NANP_HUMAN NANP_HUMAN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w4m ConSurf].
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w4m ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
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==See Also==
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*[[Acid phosphatase 3D structures|Acid phosphatase 3D structures]]
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Human]]
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[[Category: Homo sapiens]]
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[[Category: N-acylneuraminate-9-phosphatase]]
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[[Category: Large Structures]]
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[[Category: Arrowsmith, C H]]
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[[Category: Arrowsmith CH]]
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[[Category: Bountra, C]]
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[[Category: Bountra C]]
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[[Category: Cocking, R]]
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[[Category: Cocking R]]
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[[Category: Delft, F von]]
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[[Category: Edwards A]]
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[[Category: Edwards, A]]
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[[Category: Muniz JRC]]
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[[Category: Muniz, J R.C]]
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[[Category: Oppermann U]]
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[[Category: Oppermann, U]]
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[[Category: Pike ACW]]
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[[Category: Pike, A C.W]]
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[[Category: Roos A]]
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[[Category: Roos, A]]
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[[Category: Ugochukwu E]]
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[[Category: Ugochukwu, E]]
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[[Category: Weigelt J]]
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[[Category: Weigelt, J]]
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[[Category: Yue WW]]
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[[Category: Yue, W W]]
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[[Category: Von Delft F]]
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[[Category: Carbohydrate metabolism]]
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[[Category: Hdhd4]]
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[[Category: Hydrolase]]
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[[Category: Magnesium]]
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[[Category: N-acetylneuraminate]]
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[[Category: N-acetylneuraminic acid phosphatase]]
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[[Category: Nanp]]
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[[Category: Neu5ac-9- phosphate]]
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[[Category: Sialic acid]]
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Current revision

The Crystal Structure of human N-acetylneuraminic acid phosphatase, NANP

PDB ID 2w4m

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