This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.


Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2w7t

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (15:47, 13 December 2023) (edit) (undo)
 
(One intermediate revision not shown.)
Line 1: Line 1:
==Trypanosoma brucei CTPS - glutaminase domain with bound acivicin==
==Trypanosoma brucei CTPS - glutaminase domain with bound acivicin==
-
<StructureSection load='2w7t' size='340' side='right' caption='[[2w7t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
+
<StructureSection load='2w7t' size='340' side='right'caption='[[2w7t]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[2w7t]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Trypanosoma_(trypanozoon)_brucei Trypanosoma (trypanozoon) brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7T OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2W7T FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[2w7t]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Trypanosoma_brucei Trypanosoma brucei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W7T OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W7T FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
-
<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=5CS:2-AMINO-3-(CYSTEIN-S-YL)-ISOXAZOLIDIN-5-YL-ACETIC+ACID'>5CS</scene></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=5CS:2-AMINO-3-(CYSTEIN-S-YL)-ISOXAZOLIDIN-5-YL-ACETIC+ACID'>5CS</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/CTP_synthase_(glutamine_hydrolyzing) CTP synthase (glutamine hydrolyzing)], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.4.2 6.3.4.2] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7t OCA], [https://pdbe.org/2w7t PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w7t RCSB], [https://www.ebi.ac.uk/pdbsum/2w7t PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7t ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2w7t FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w7t OCA], [http://pdbe.org/2w7t PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2w7t RCSB], [http://www.ebi.ac.uk/pdbsum/2w7t PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2w7t ProSAT]</span></td></tr>
+
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q4GZ95_TRYB2 Q4GZ95_TRYB2] Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen.[RuleBase:RU810713]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Line 21: Line 22:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Arrowsmith, C H]]
+
[[Category: Large Structures]]
-
[[Category: Berg, S Van Den]]
+
[[Category: Trypanosoma brucei]]
-
[[Category: Berglund, H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Bountra, C]]
+
[[Category: Berglund H]]
-
[[Category: Collins, R]]
+
[[Category: Bountra C]]
-
[[Category: Dahlgren, L G]]
+
[[Category: Collins R]]
-
[[Category: Edwards, A M]]
+
[[Category: Dahlgren LG]]
-
[[Category: Flodin, S]]
+
[[Category: Edwards AM]]
-
[[Category: Flores, A]]
+
[[Category: Flodin S]]
-
[[Category: Graslund, S]]
+
[[Category: Flores A]]
-
[[Category: Hammarstrom, M]]
+
[[Category: Graslund S]]
-
[[Category: Johansson, A]]
+
[[Category: Hammarstrom M]]
-
[[Category: Johansson, I]]
+
[[Category: Johansson A]]
-
[[Category: Karlberg, T]]
+
[[Category: Johansson I]]
-
[[Category: Kotenyova, T]]
+
[[Category: Karlberg T]]
-
[[Category: Lehtio, L]]
+
[[Category: Kotenyova T]]
-
[[Category: Moche, M]]
+
[[Category: Lehtio L]]
-
[[Category: Nilsson, M E]]
+
[[Category: Moche M]]
-
[[Category: Nordlund, P]]
+
[[Category: Nilsson ME]]
-
[[Category: Nyman, T]]
+
[[Category: Nordlund P]]
-
[[Category: Persson, C]]
+
[[Category: Nyman T]]
-
[[Category: Structural genomic]]
+
[[Category: Persson C]]
-
[[Category: Sagemark, J]]
+
[[Category: Sagemark J]]
-
[[Category: Schueler, H]]
+
[[Category: Schueler H]]
-
[[Category: Siponen, M I]]
+
[[Category: Siponen MI]]
-
[[Category: Thorsell, A G]]
+
[[Category: Thorsell AG]]
-
[[Category: Tresaugues, L]]
+
[[Category: Tresaugues L]]
-
[[Category: Weigelt, J]]
+
[[Category: Van Den Berg S]]
-
[[Category: Welin, M]]
+
[[Category: Weigelt J]]
-
[[Category: Wikstrom, M]]
+
[[Category: Welin M]]
-
[[Category: Wisniewska, M]]
+
[[Category: Wikstrom M]]
-
[[Category: Glutaminase domain]]
+
[[Category: Wisniewska M]]
-
[[Category: Ligase]]
+

Current revision

Trypanosoma brucei CTPS - glutaminase domain with bound acivicin

PDB ID 2w7t

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Personal tools