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2w8h
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 2w8h is ON HOLD until sometime in the future Authors: Hagelueken, G., Ingledew, W.J., Huang, H., Petrovic-Stojanovska, B., Whitfield, C., ElMkami, H...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Crystal structure of spin labeled Wza24-345.== | |
| + | <StructureSection load='2w8h' size='340' side='right'caption='[[2w8h]], [[Resolution|resolution]] 2.76Å' scene=''> | ||
| + | == Structural highlights == | ||
| + | <table><tr><td colspan='2'>[[2w8h]] is a 8 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2W8H OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2W8H FirstGlance]. <br> | ||
| + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.76Å</td></tr> | ||
| + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=MTN:S-[(1-OXYL-2,2,5,5-TETRAMETHYL-2,5-DIHYDRO-1H-PYRROL-3-YL)METHYL]+METHANESULFONOTHIOATE'>MTN</scene></td></tr> | ||
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2w8h FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2w8h OCA], [https://pdbe.org/2w8h PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2w8h RCSB], [https://www.ebi.ac.uk/pdbsum/2w8h PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2w8h ProSAT]</span></td></tr> | ||
| + | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9X4B7_ECOLX Q9X4B7_ECOLX] | ||
| + | == Evolutionary Conservation == | ||
| + | [[Image:Consurf_key_small.gif|200px|right]] | ||
| + | Check<jmol> | ||
| + | <jmolCheckbox> | ||
| + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/w8/2w8h_consurf.spt"</scriptWhenChecked> | ||
| + | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
| + | <text>to colour the structure by Evolutionary Conservation</text> | ||
| + | </jmolCheckbox> | ||
| + | </jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2w8h ConSurf]. | ||
| + | <div style="clear:both"></div> | ||
| + | <div style="background-color:#fffaf0;"> | ||
| + | == Publication Abstract from PubMed == | ||
| + | Distance fingerprinting: Pulsed electron-electron double resonance spectroscopy (PELDOR) is applied to the octameric membrane protein complex Wza of E. coli. The data yielded a detailed distance fingerprint of its periplasmic region that compares favorably to the crystal structure. These results provide the foundation to study conformation changes from interaction with partner proteins. | ||
| - | + | PELDOR Spectroscopy Distance Fingerprinting of the Octameric Outer-Membrane Protein Wza from Escherichia coli.,Hagelueken G, Ingledew WJ, Huang H, Petrovic-Stojanovska B, Whitfield C, Elmkami H, Schiemann O, Naismith JH Angew Chem Int Ed Engl. 2009 Mar 17;48(16):2904-2906. PMID:19294709<ref>PMID:19294709</ref> | |
| - | + | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | |
| - | + | </div> | |
| - | + | <div class="pdbe-citations 2w8h" style="background-color:#fffaf0;"></div> | |
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Escherichia coli]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: ElMkami H]] | ||
| + | [[Category: Hagelueken G]] | ||
| + | [[Category: Huang H]] | ||
| + | [[Category: Ingledew WJ]] | ||
| + | [[Category: Naismith JH]] | ||
| + | [[Category: Petrovic-Stojanovska B]] | ||
| + | [[Category: Schiemann O]] | ||
| + | [[Category: Whitfield C]] | ||
Current revision
Crystal structure of spin labeled Wza24-345.
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