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2wh5
From Proteopedia
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==Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA== | ==Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA== | ||
| - | <StructureSection load='2wh5' size='340' side='right' caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> | + | <StructureSection load='2wh5' size='340' side='right'caption='[[2wh5]], [[Resolution|resolution]] 2.60Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2wh5]] is a 6 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WH5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WH5 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6Å</td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=COA:COENZYME+A'>COA</scene>, <scene name='pdbligand=ST9:STEAROYL-COENZYME+A'>ST9</scene>, <scene name='pdbligand=STE:STEARIC+ACID'>STE</scene></td></tr> |
| + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wh5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wh5 OCA], [https://pdbe.org/2wh5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wh5 RCSB], [https://www.ebi.ac.uk/pdbsum/2wh5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wh5 ProSAT]</span></td></tr> | ||
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/ACBD4_HUMAN ACBD4_HUMAN] Binds medium- and long-chain acyl-CoA esters and may function as an intracellular carrier of acyl-CoA esters. |
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
Check<jmol> | Check<jmol> | ||
<jmolCheckbox> | <jmolCheckbox> | ||
| - | <scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/2wh5_consurf.spt"</scriptWhenChecked> | + | <scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wh/2wh5_consurf.spt"</scriptWhenChecked> |
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | <scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked> | ||
<text>to colour the structure by Evolutionary Conservation</text> | <text>to colour the structure by Evolutionary Conservation</text> | ||
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__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Homo sapiens]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Arrowsmith C]] |
| - | [[Category: | + | [[Category: Bountra C]] |
| - | [[Category: | + | [[Category: Chaikuad A]] |
| - | [[Category: Edwards | + | [[Category: Edwards A]] |
| - | [[Category: Johansson | + | [[Category: Johansson C]] |
| - | [[Category: Oppermann | + | [[Category: Oppermann U]] |
| - | [[Category: Roos | + | [[Category: Roos AK]] |
| - | [[Category: Salah | + | [[Category: Salah E]] |
| - | [[Category: Savitsky | + | [[Category: Savitsky P]] |
| - | [[Category: Shafqat | + | [[Category: Shafqat N]] |
| - | [[Category: Ugochukwu | + | [[Category: Ugochukwu E]] |
| - | [[Category: Weigelt | + | [[Category: Weigelt J]] |
| - | [[Category: Yue | + | [[Category: Yue WW]] |
| - | [[Category: | + | [[Category: Von Delft F]] |
| - | + | ||
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Current revision
Crystal structure of human acyl-CoA binding domain 4 complexed with stearoyl-CoA
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Categories: Homo sapiens | Large Structures | Arrowsmith C | Bountra C | Chaikuad A | Edwards A | Johansson C | Oppermann U | Roos AK | Salah E | Savitsky P | Shafqat N | Ugochukwu E | Weigelt J | Yue WW | Von Delft F
