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2wkw

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==Alcaligenes esterase complexed with product analogue==
==Alcaligenes esterase complexed with product analogue==
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<StructureSection load='2wkw' size='340' side='right' caption='[[2wkw]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
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<StructureSection load='2wkw' size='340' side='right'caption='[[2wkw]], [[Resolution|resolution]] 2.03&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2wkw]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Alcsp Alcsp]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WKW OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2WKW FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2wkw]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Alcaligenes_sp. Alcaligenes sp.]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2WKW OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2WKW FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=W22:[(2S)-4-METHYL-3-OXO-2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-2-YL]ACETIC+ACID'>W22</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.03&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1qlw|1qlw]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=W22:[(2S)-4-METHYL-3-OXO-2,3,4,5-TETRAHYDRO-1H-1,4-BENZODIAZEPIN-2-YL]ACETIC+ACID'>W22</scene></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2wkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wkw OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2wkw RCSB], [http://www.ebi.ac.uk/pdbsum/2wkw PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2wkw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2wkw OCA], [https://pdbe.org/2wkw PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2wkw RCSB], [https://www.ebi.ac.uk/pdbsum/2wkw PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2wkw ProSAT]</span></td></tr>
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<table>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7SIA5_ALCSP Q7SIA5_ALCSP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/2wkw_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/wk/2wkw_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2wkw ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2wkw" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Carboxylesterase|Carboxylesterase]]
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*[[Carboxylesterase 3D structures|Carboxylesterase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Alcsp]]
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[[Category: Alcaligenes sp]]
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[[Category: Bourne, P C.]]
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[[Category: Large Structures]]
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[[Category: Isupov, M N.]]
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[[Category: Bourne PC]]
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[[Category: Littlechild, J A.]]
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[[Category: Isupov MN]]
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[[Category: Alpha/beta hydrolase]]
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[[Category: Littlechild JA]]
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[[Category: Atomic resolution]]
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[[Category: Esterase]]
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[[Category: Hydrolase]]
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Current revision

Alcaligenes esterase complexed with product analogue

PDB ID 2wkw

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