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5ohx

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==Structure of active cystathionine B-synthase from Apis mellifera==
==Structure of active cystathionine B-synthase from Apis mellifera==
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<StructureSection load='5ohx' size='340' side='right' caption='[[5ohx]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
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<StructureSection load='5ohx' size='340' side='right'caption='[[5ohx]], [[Resolution|resolution]] 3.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5ohx]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Apime Apime]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OHX OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OHX FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5ohx]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Apis_mellifera Apis mellifera]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OHX OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OHX FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.2&#8491;</td></tr>
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<tr id='gene'><td class="sblockLbl"><b>[[Gene|Gene:]]</b></td><td class="sblockDat">AmCBS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=7460 APIME])</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>, <scene name='pdbligand=PLP:PYRIDOXAL-5-PHOSPHATE'>PLP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5ohx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ohx OCA], [http://pdbe.org/5ohx PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5ohx RCSB], [http://www.ebi.ac.uk/pdbsum/5ohx PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5ohx ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5ohx FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5ohx OCA], [https://pdbe.org/5ohx PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5ohx RCSB], [https://www.ebi.ac.uk/pdbsum/5ohx PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5ohx ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CBS_APIME CBS_APIME] Hydro-lyase catalyzing the first step of the transsulfuration pathway, where the hydroxyl group of L-serine is displaced by L-homocysteine in a beta-replacement reaction to form L-cystathionine, the precursor of L-cysteine.<ref>PMID:29275181</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5ohx" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5ohx" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Cystathionine β-synthase 3D structures|Cystathionine β-synthase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Apime]]
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[[Category: Apis mellifera]]
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[[Category: Ereno-Orbea, J]]
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[[Category: Large Structures]]
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[[Category: Gimenez-Mascarell, P]]
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[[Category: Ereno-Orbea J]]
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[[Category: Klaudiny, J]]
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[[Category: Gimenez-Mascarell P]]
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[[Category: Kraus, J P]]
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[[Category: Klaudiny J]]
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[[Category: Majtan, J]]
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[[Category: Kraus JP]]
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[[Category: Majtan, T]]
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[[Category: Majtan J]]
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[[Category: Martinez-Cruz, L A]]
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[[Category: Majtan T]]
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[[Category: Oyenarte, I]]
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[[Category: Martinez-Cruz LA]]
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[[Category: Adomet]]
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[[Category: Oyenarte I]]
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[[Category: Cb]]
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[[Category: H2]]
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[[Category: Homocystinuria]]
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[[Category: Hydrogen sulfide]]
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[[Category: Lyase]]
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[[Category: S-adenosylmethionine]]
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[[Category: Transsulfuration]]
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Current revision

Structure of active cystathionine B-synthase from Apis mellifera

PDB ID 5ohx

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