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5or9

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(New page: ==Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13== <StructureSection load='5or9' size='340' side='right' caption='5or9, [[Resolution|re...)
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==Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13==
==Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13==
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<StructureSection load='5or9' size='340' side='right' caption='[[5or9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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<StructureSection load='5or9' size='340' side='right'caption='[[5or9]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[5or9]] is a 1 chain structure. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OR9 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5OR9 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[5or9]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=5OR9 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=5OR9 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JR5:(2~{S})-1-(4-fluorophenyl)sulfonyl-~{N}-(2-methyl-5,6-dihydro-4~{H}-cyclopenta[c]pyrazol-3-yl)pyrrolidine-2-carboxamide'>JR5</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[5or8|5or8]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=JR5:(2~{S})-1-(4-fluorophenyl)sulfonyl-~{N}-(2-methyl-5,6-dihydro-4~{H}-cyclopenta[c]pyrazol-3-yl)pyrrolidine-2-carboxamide'>JR5</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=5or9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5or9 OCA], [http://pdbe.org/5or9 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=5or9 RCSB], [http://www.ebi.ac.uk/pdbsum/5or9 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=5or9 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=5or9 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=5or9 OCA], [https://pdbe.org/5or9 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=5or9 RCSB], [https://www.ebi.ac.uk/pdbsum/5or9 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=5or9 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN]] May play a role in transcriptional regulation interacting with ISWI.
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[https://www.uniprot.org/uniprot/BAZ2B_HUMAN BAZ2B_HUMAN] May play a role in transcriptional regulation interacting with ISWI.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 5or9" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 5or9" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Bromodomain adjacent to zinc finger 3D structures|Bromodomain adjacent to zinc finger 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Caflisch, A]]
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[[Category: Homo sapiens]]
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[[Category: Lolli, G]]
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[[Category: Large Structures]]
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[[Category: Marchand, J R]]
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[[Category: Caflisch A]]
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[[Category: Vedove, A D]]
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[[Category: Lolli G]]
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[[Category: Four helical bundle]]
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[[Category: Marchand J-R]]
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[[Category: Transcription]]
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[[Category: Vedove AD]]

Current revision

Crystal Structure of BAZ2B bromodomain in complex with 1-methyl-cyclopentapyrazole compound 13

PDB ID 5or9

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