This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


Sigma factor 3D structures

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
(New page: ==3D structures of sigma factor== Updated on {{REVISIONDAY2}}-{{MONTHNAME|{{REVISIONMONTH}}}}-{{REVISIONYEAR}} {{#tree:id=OrganizedByTopic|openlevels=0| *Sigma factor **1ku2 – TaS...)
Current revision (15:39, 16 December 2023) (edit) (undo)
 
(11 intermediate revisions not shown.)
Line 6: Line 6:
*Sigma factor
*Sigma factor
-
**[[1ku2]] – TaSF region 1.2-3.1 – ''Thermus aquaticus''<br />
+
**[[1ku2]] – TaSF-A region 1.2-3.1 – ''Thermus aquaticus''<br />
-
**[[1ku3]] – TaSF region 4 (mutant)<br />
+
**[[1ku3]] – TaSF-A region 4 (mutant)<br />
-
**[[3les]] – TaSF residues 93-271<br />
+
**[[3les]] – TaSF-A residues 93-271<br />
-
**[[1sig]] – EcSF – ''Escherichia coli''<br />
+
**[[1sig]] – EcSF-70 – ''Escherichia coli''<br />
-
**[[2mao]] – EcSF region 2 - NMR<br />
+
**[[2mao]] – EcSF-E region 2 - NMR<br />
-
**[[6fi7]] – EcSF-S - NMR<br />
+
**[[6fi7]] – EcSF-38 - NMR<br />
**[[1tty]] – TmSF-70 region 4 – ''Thermotoga maritima''<br />
**[[1tty]] – TmSF-70 region 4 – ''Thermotoga maritima''<br />
**[[2k6x]] – TmSF-70 region 1.1 (mutant) - NMR<br />
**[[2k6x]] – TmSF-70 region 1.1 (mutant) - NMR<br />
**[[2ahq]] – AaSF-54 C terminal – ''Aquifex aeolicus'' - NMR<br />
**[[2ahq]] – AaSF-54 C terminal – ''Aquifex aeolicus'' - NMR<br />
**[[2k9l]], [[2k9m]] – AaSF-54 core domain - NMR<br />
**[[2k9l]], [[2k9m]] – AaSF-54 core domain - NMR<br />
-
**[[3mzy]] – SF-H – ''Fusobacterium nucleatum''<br />
+
**[[3mzy]] – SFH – ''Fusobacterium nucleatum''<br />
**[[1h3l]] – ScSF N terminal – ''Streptomyces coelicolor''<br />
**[[1h3l]] – ScSF N terminal – ''Streptomyces coelicolor''<br />
**[[5fgm]] – ScSF-R region 4<br />
**[[5fgm]] – ScSF-R region 4<br />
 +
**[[7qh5]] – SF-G1 – ''Streptomyces tsukubensis''<br />
**[[5mww]] – BsSF-A region 1.1 - ''Bacillus subtilis'' - NMR <br />
**[[5mww]] – BsSF-A region 1.1 - ''Bacillus subtilis'' - NMR <br />
 +
**[[8b3z]] – BsSF-E N terminal <br />
**[[5xe7]] – MtSF-J – ''Mycobacterium tuberculosis''<br />
**[[5xe7]] – MtSF-J – ''Mycobacterium tuberculosis''<br />
*Sigma factor complex with DNA
*Sigma factor complex with DNA
-
**[[3ugo]], [[3ugp]] - TaSF region 2 + DNA<br />
+
**[[3ugo]], [[3ugp]] - TaSF-A region 2 + DNA<br />
-
**[[4ki2]] - TaSF region 2-3 + DNA<br />
+
**[[1ku7]] – TaSF-A region 4 (mutant) + DNA <br />
 +
**[[4ki2]] - TaSF-A region 2-3 + DNA<br />
**[[2h27]] – EcSF-E region 4 + DNA<br />
**[[2h27]] – EcSF-E region 4 + DNA<br />
-
**[[2map]] – EcSF region 2 + DNA - NMR<br />
+
**[[2map]] – EcSF-E region 2 + DNA - NMR<br />
-
**[[1ku7]] – EcSF region 4 (mutant) + DNA <br />
+
**[[2o8k]], [[2o9l]] – AaSF-54 C terminal + DNA - NMR<br />
**[[2o8k]], [[2o9l]] – AaSF-54 C terminal + DNA - NMR<br />
-
**[[5ui5]] – AaSF RpoN residues 61-398 + DNA <br />
+
**[[5ui5]] – AaSF-54 residues 61-398 + DNA <br />
**[[6jhe]] – BsSF-W region 4 + DNA <br />
**[[6jhe]] – BsSF-W region 4 + DNA <br />
Line 37: Line 39:
**[[1tlh]] – EcSF-70 region 4 + anti-σ factor<br />
**[[1tlh]] – EcSF-70 region 4 + anti-σ factor<br />
**[[1rp3]], [[1sc5]] – AaSF-28 + anti-σ factor FLGM <br />
**[[1rp3]], [[1sc5]] – AaSF-28 + anti-σ factor FLGM <br />
-
**[[6ivu]] – SF-1 + anti-σ factor – ''Clostridium thermocellum''<br />
+
**[[6ivu]] – CtSF-1 + anti-σ factor – ''Clostridium thermocellum''<br />
**[[5wur]] – BsSF-W + anti-σ factor <br />
**[[5wur]] – BsSF-W + anti-σ factor <br />
**[[5uxx]] – SF + anti-σ factor – ''Bartonella quintana''<br />
**[[5uxx]] – SF + anti-σ factor – ''Bartonella quintana''<br />
Line 44: Line 46:
*Sigma factor complex with protein
*Sigma factor complex with protein
-
**[[3lev]] – TaSF residues 93-271 + antibody<br />
+
**[[3lev]] – TaSF-A residues 93-271 + antibody<br />
-
**[[1l9u]] – TaSF region 1.1-4 + RNAP subunits α,β,β’,ω<br />
+
**[[1l9u]] – TaSF-A region 1.1-4 + RNAP subunits α,β,β’,ω<br />
**[[1or7]] – EcSF-E + σ-E factor negative regulatory protein <br />
**[[1or7]] – EcSF-E + σ-E factor negative regulatory protein <br />
-
**[[4lup]] – EcSF residues 3-92 + EcSF region 2 <br />
+
**[[4lup]] – EcSF-E residues 3-92 + EcSF region 2 <br />
-
**[[2p7v]] – EcSF ProD region 4 + regulator of σ D<br />
+
**[[2p7v]] – EcSF-70 region 4 + regulator of σ D<br />
-
**[[4yg2]], [[5uag]], [[5uaj]], [[5uaq]] – EcSF ProD + RNAP subunits α,β,β’,ω <br />
+
**[[4yg2]], [[5uag]], [[5uaj]], [[5uaq]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />
**[[5ui8]] – EcSF-45 + RNAP subunits α,β,β’,ω <br />
**[[5ui8]] – EcSF-45 + RNAP subunits α,β,β’,ω <br />
-
**[[4mex]], [[4kmu]], [[4kn4]], [[4kn7]], [[5uac]], [[5uah]], [[5ual]], [[4zh3]], [[4zh4]] – EcSF ProD + RNAP subunits α,β,β’,ω + antibiotic <br />
+
**[[6byu]] – EcSF-70 + RNAP subunits α,β,β’,ω + ppApp <br />
-
**[[4xsx]], [[4xsy]], [[4xsz]] – EcSF ProD + RNAP subunits α,β,β’,ω + antibiotic <br />
+
**[[4mey]], [[4ljz]], [[4lk1]], [[6cux]] – EcSF-70 + RNAP subunits α,β,β’,ω <br />
-
**[[6byu]] – EcSF ProD + RNAP subunits α,β,β’,ω + ppApp <br />
+
**[[6c9y]], [[6ca0]] – EcSF-70 + RNAP subunits α,β,β’,ω - Cryo EM<br />
-
**[[4mey]], [[4ljz]], [[4lk1]], [[6cux]] – EcSF ProD + RNAP subunits α,β,β’,ω <br />
+
-
**[[6c9y]], [[6ca0]] – EcSF ProD + RNAP subunits α,β,β’,ω - Cryo EM<br />
+
-
**[[5byh]] – EcSF-45 + RNAP subunits α,β,β’,ω <br />
+
**[[5nwt]] – EcSF-54 + RNAP subunits α,β,β’,ω <br />
**[[5nwt]] – EcSF-54 + RNAP subunits α,β,β’,ω <br />
-
**[[5w1s]] – EcSF RpoD + RNAP subunits α,β,β’ + TraR<br />
+
**[[5w1s]] – EcSF-70 + RNAP subunits α,β,β’ + TraR<br />
-
**[[5vsw]] – EcSF RpoD + RNAP subunits α,β,β’ + DnaK suppressor protein<br />
+
**[[5vsw]] – EcSF-70 + RNAP subunits α,β,β’ + DnaK suppressor protein<br />
-
**[[5w1t]] – EcSF RpoD + RNAP subunits α,β,β’ + RpoZ + DnaK suppressor protein<br />
+
**[[5w1t]] – EcSF-70 + RNAP subunits α,β,β’ + RpoZ + DnaK suppressor protein<br />
-
**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF ProD + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
+
**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
**[[3hug]] – MtSF-L + membrane protein <br />
**[[3hug]] – MtSF-L + membrane protein <br />
**[[4x8k]] – MtSF-A region 2 + RBPA<br />
**[[4x8k]] – MtSF-A region 2 + RBPA<br />
**[[6onu]], [[6ono]] – MtSF-A region 4 + WHIB1<br />
**[[6onu]], [[6ono]] – MtSF-A region 4 + WHIB1<br />
**[[5zx3]] – MtSF-H + RNAP subunits α,β,β’,ω <br />
**[[5zx3]] – MtSF-H + RNAP subunits α,β,β’,ω <br />
-
**[[6fbv]] – MtSF-A + RNAP subunits α,β,β’,ω - SP Cryo EM<br />
+
**[[6fbv]] – MtSF-A + RNAP subunits α,β,β’,ω - Cryo EM<br />
 +
**[[7pp4]], [[7q4u]], [[7q59]], [[7zf2]] – MtSF-B + RNAP subunits α,β,β’,ω - Cryo EM<br />
**[[6c05]], [[6c06]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA - Cryo EM<br />
**[[6c05]], [[6c06]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA - Cryo EM<br />
-
**[[3wod]], [[2a6e]], [[2cw0]], [[5tmf]] – TtSF + RNAP subunits α,β,β’,ω - ''Thermus thermophilus'' <br />
+
**[[3wod]], [[2a6e]], [[2cw0]], [[5tmf]] – TtSF-A + RNAP subunits α,β,β’,ω - ''Thermus thermophilus'' <br />
-
**[[4mq9]], [[2a68]], [[2a69]], [[2a6h]], [[3dxj]], [[3eql]] – TtSF ProD + RNAP subunits α,β,β’,ω + antibiotic <br />
+
**[[2be5]] – TtSF-70 + RNAP subunits α,β,β’,ω + inhibitor<br />
-
**[[2be5]] – TtSF + RNAP subunits α,β,β’,ω + inhibitor<br />
+
**[[6pfj]], [[6pfv]] – ScSF (mutant) + AMFC protein<br />
**[[6pfj]], [[6pfv]] – ScSF (mutant) + AMFC protein<br />
**[[5tmc]] – TtSF-A + RNAP subunits α,β,β’,ω + protein + G4P<br />
**[[5tmc]] – TtSF-A + RNAP subunits α,β,β’,ω + protein + G4P<br />
**[[5xj0]] – TtSF-A + RNAP subunits α,β,β’,ω + GP39 + GP76<br />
**[[5xj0]] – TtSF-A + RNAP subunits α,β,β’,ω + GP39 + GP76<br />
**[[5x22]] – TtSF-A + RNAP subunits α,β,β’,ω + GpA + CMPcPP<br />
**[[5x22]] – TtSF-A + RNAP subunits α,β,β’,ω + GpA + CMPcPP<br />
-
**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF ProD + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
+
**[[4lk0]], [[4llg]], [[4yfk]], [[4yfn]], [[4yfx]], [[4zh2]] – EcSF7-0 + EcRNAP subunits α,β,β’,ω + RNAP inhibitor<br />
**[[4cxf]] – SF CNRH + CNRY – ''Cupriavidus metallidurans''<br />
**[[4cxf]] – SF CNRH + CNRY – ''Cupriavidus metallidurans''<br />
-
**[[4g6d]], [[4g8x]], [[4g94]] – SF ProD region 4 + Orf067 – ''Staphylococcus aureus''<br />
+
**[[4g6d]], [[4g8x]], [[4g94]] – SF-70 region 4 + Orf067 – ''Staphylococcus aureus''<br />
-
**[[5yix]] – SF RpoD + GCRA - ''Caulobacter crescentus''<br />
+
**[[5yix]] – CcSF-70 + GcrA - ''Caulobacter crescentus''<br />
-
**[[6in7]] – SF-H + ALGU – Pseudomonas aeruginosa<br />
+
**[[6in7]] – PaSF-H + ALGU – ''Pseudomonas aeruginosa''<br />
-
**[[6eyd]] – SF-A + RNAP subunits α,β,β’,ω - ''Mycobacterium smegmatis'' – Cryo EM <br />
+
**[[6eyd]] – MsSF-A + RNAP subunits α,β,β’,ω - ''Mycobacterium smegmatis'' – Cryo EM <br />
-
**[[6dxo]] – SF-A + BLDN – ''Streptomyces venezuelae''<br />
+
**[[6dxo]] – SvSF-A + BLDN – ''Streptomyces venezuelae''<br />
 +
**[[7vf9]] – PaSF-38 + RNAP subunits α,β,β’,ω - Cryo EM<br />
-
*Sigma factor complex with protein and DNA and RNA
+
*E. coli sigma factor-70 complex with protein, DNA and RNA
-
**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]] – TtSF SIGA + RNAP subunits α,β,β’,ω + DNA<br />
+
**[[6p1k]], [[7khb]] – EcSF-70 + EcRNAP subunits α,β,β’,ω - Cryo EM<br />
-
**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />
+
**[[6vjs]] – EcSF-70 + EcRNAP subunits α,β,β’,ω <br />
-
**[[6p71]], [[6p70]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]] – TtSF + RNAP subunits α,β,β’,ω + DNA + RNA<br />
+
**[[3iyd]] – EcSF-70 in transcription initiation complex + catabolite gene activator<br />
-
**[[5voi]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA <br />
+
-
**[[5d4c]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + CTP + ATP<br />
+
-
**[[5d4d]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + CTP + NAD<br />
+
-
**[[5d4e]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + CTP + dephosphate-CoA<br />
+
-
**[[3n97]] – TaSF region 4 + RNAP subunits α + DNA<br />
+
-
**[[4xlp]], [[4xlq]], [[5tjg]] – TaSF SIGA + RNAP subunits α,β,β’,ω + DNA <br />
+
-
**[[1l9z]] – TaSF + RNAP subunits α,β,β’,ω + DNA – Cryo EM <br />
+
-
**[[4xlr]], [[4xls]] – TaSF-A + RNAP subunits α,β,β’,ω + CarD-like transcriptional regulator + DNA <br />
+
-
**[[1rio]] - TaSF region 4 + repression protein CI + DNA<br />
+
-
**[[3iyd]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + catabolite gene activator + DNA<br />
+
**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />
**[[4jk1]], [[4jk2]], [[4jkr]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P<br />
-
**[[4yln]], [[4ylo]], [[4ylp]], [[6n62]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA<br />
+
**[[7khe]], [[7khi]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + G4P – Cryo EM<br />
 +
**[[7khc]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + POP – Cryo EM<br />
 +
**[[4yln]], [[4ylo]], [[4ylp]], [[6n62]], [[6utv]], [[6utw]], [[6utx]] [[6uty]], [[6utz]], [[6uu0]], [[6uu1]], [[6uuc]] [[6uu3]], [[6uu4]], [[6uu5]], [[6uu6]], [[6uu7]], [[6uu8]], [[6uu2]], [[6uua]], [[6uuc]] – EcSF-70 in transcription initiation complex<br />
 +
**[[6b6h]], [[6xl5]], [[6xl9]], [[6xlj]], [[6xll]], [[7vwy]], [[8igr]], [[8igs]] – EcSF-70 in transcription activation complex - Cryo EM<br />
**[[5nss]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM<br />
**[[5nss]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + phage shock protein F + DNA - Cryo EM<br />
-
**[[5nsr]], [[6gh6]], [[6gh5]], [[6gfw]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
+
**[[5nsr]], [[6gh6]], [[6gh5]], [[6gfw]], [[7szk]] – EcSF-54 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
 +
**[[7bef]], [[7beg]], [[7chw]], [[7mkd]], [[7mke]], [[7mki]], [[7mkj]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
**[[6n61]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA<br />
**[[6n61]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + capistruin + DNA<br />
**[[6n60]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA<br />
**[[6n60]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + microcin + DNA<br />
-
**[[6p18]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + protein Q + DNA + RNA<br />
+
**[[6p18]] – EcSF-70 in transcription antitermination complex + protein Q<br />
-
**[[6jnx]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + protein Q + DNA + RNA – Cryo EM<br />
+
**[[6jnx]], [[7ubm]] – EcSF-70 in transcription antitermination complex + protein Q – Cryo EM<br />
-
**[[6jbq]] – EcSF-E + EcRNAP subunits α,β,β’,ω + DNA + RNA – Cryo EM<br />
+
**[[7ubn]] – EcSF-70 in transcription antitermination complex + NusA – Cryo EM<br />
 +
**[[6jbq]] – EcSF-E in transcription initiation complex – Cryo EM<br />
**[[5vt0]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM<br />
**[[5vt0]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + RNA – Cryo EM<br />
**[[6k4y]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM<br />
**[[6k4y]] – EcSF-70 + EcRNAP subunits α,β,β’,ω + anti-SF + MOTA + DNA – Cryo EM<br />
-
**[[6dcf]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA<br />
+
**[[6ldi]], [[6xh7]], [[6xh8]], [[7c17]] – EcSF-70 in transcription activation complex + CueR – Cryo EM<br />
-
**[[6m7j]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA – Cryo EM<br />
+
**[[6pb4]], [[6pb5]], [[6pb6]] – EcSF-70 in transcription activation complex + Crp – Cryo EM<br />
-
**[[6eec]], [[6ee8]], [[6edt]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + CARD + DNA – Cryo EM<br />
+
**[[7vwz]] – EcSF-70 in transcription activation complex + right origin-binding protein – Cryo EM<br />
-
**[[6jcy]], [[6jcx]] – MtSF-H + RNAP subunits α,β,β’,ω + DNA + RNA<br />
+
**[[7w5w]], [[7w5x]], [[7w5y]] – EcSF-70 in transcription activation complex + SoxS – Cryo EM<br />
-
**[[6dve]], [[6dvd]] – MtSF-L + RNAP subunits α,β,β’,ω + DNA<br />
+
**[[8jo2]] – EcSF-70 in transcription activation complex + BasR – Cryo EM<br />
-
**[[5zx2]] – MtSF-H + RNAP subunits α,β,β’,ω + DNA + RNA<br />
+
**[[6n57]], [[6n58]] – EcSF-70 in transcription initiation complex + Tsar – Cryo EM<br />
-
**[[6dvc]], [[6dvb]], [[6dv9]] – MtSF-L + RNAP subunits α,β,β’,ω + DNA + RNA<br />
+
**[[6psq]], [[6psr]], [[6pss]], [[6pst]], [[6psu]], [[6psv]], [[6psw]] – EcSF-70 in transcription initiation complex + Trar – Cryo EM<br />
-
**[[5uha]] – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA <br />
+
**[[6n4c]], [[6oul]] – EcSF-70 in transcription initiation complex – Cryo EM<br />
-
**[[6c04]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM<br />
+
**[[7khe]] – EcSF-70 in transcription initiation complex + GTP – Cryo EM<br />
-
**[[5uhe]], [[5uhf]] – MtSF SIGA + MtRNAP subunits α,β,β’,ω + DNA + inhibitor<br />
+
**[[7chw]], [[7khb]] – EcSF-70 in transcription open promoter complex – Cryo EM<br />
-
**[[5tw1]], [[6cce]] – MsSF-A + MtRNAP subunits α,β,β’,ω + DNA + peptide - ''Mycobacterium smegmatis''<br />
+
**[[6wmu]], [[7c97]], [[7dy6]] – EcSF-70 in transcription open promoter complex + SspA – Cryo EM<br />
-
**[[5vi8]] – MsSF-A + MsRNAP subunits α,β,β’,ω + DNA <br />
+
**[[7khi]] – EcSF-70 in transcription open promoter complex + DKSA + G4P – Cryo EM<br />
-
**[[6ccv]] – MsSF-A + MtRNAP subunits α,β,β’,ω + DNA + peptide + RbpA <br />
+
**[[7khc]] – EcSF-70 in transcription closed promoter complex – Cryo EM<br />
 +
**[[6xlm]], [[7n4e]], [[7xui]] – EcSF-70 in elongation complex – Cryo EM<br />
 +
 
 +
*Other sigma factor complex with protein, DNA and RNA
 +
 
 +
**[[4oio]], [[4g7h]], [[4g7o]], [[4g7z]], [[4q4z]], [[4q5s]], [[6p71]], [[6p70]], [[6oy7]], [[6oy6]], [[6oy5]], [[6ow3]], [[6ovy]], [[6ovr]], [[7mli]], [[7mlj]] – TtSF-A in reiterative transcription complex <br />
 +
**[[7rdq]] – TtSF-A in reiterative transcription complex – Cryo EM<br />
 +
**[[5vo8]] – TtSF-A in reiterative transcription complex + GTP<br />
 +
**[[6kqd]], [[6kqe]], [[6kqf]], [[6kqg]], [[6kqh]], [[6kql]], [[6kqm]], [[6kqn]], [[6l74]], [[6lts]], [[5e17]], [[5e18]] – TtSF-A in initial
 +
transcription complex <br />
 +
**[[6wox]], [[6woy]] – TtSF-A in initial transcription complex + CPT<br />
 +
**[[1smy]] – TtSF + RNAP subunits α,β,β’,ω + G4P<br />
 +
**[[5voi]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA <br />
 +
**[[7eh2]], [[7mlb]] – TtSF-A in transcription initiation complex <br />
 +
**[[5d4c]] – TtSF-A in transcription initiation complex + CTP + ATP<br />
 +
**[[5d4d]] – TtSF-A in transcription initiation complex + CTP + NAD<br />
 +
**[[5d4e]] – TtSF-A in transcription initiation complex + CTP + dephosphate-CoA<br />
 +
**[[5x22]], [[7eh0]], [[7eh1]] – TtSF-A in transcription initiation complex + CMPPP<br />
 +
**[[5i2d]] – TtSF-A in transcription activation complex + transcriptional regulator <br />
 +
**[[7f75]] – BsSF-A in transcription activation complex + transcriptional regulator – Cryo EM<br />
 +
**[[7ckq]] – BsSF-A in transcription activation complex + multidrug regulator + YKZG – Cryo EM<br />
 +
**[[3n97]] – TaSF-A region 4 + RNAP subunits α + DNA<br />
 +
**[[4xln]], [[4xlp]], [[4xlq]], [[5tjg]] – TaSF-A in transcription initiation complex<br />
 +
**[[1l9z]] – TaSF-A + RNAP subunits α,β,β’,ω + DNA – Cryo EM <br />
 +
**[[4xlr]], [[4xls]] – TaSF-A in transcription initiation complex + CarD-like transcriptional regulator<br />
 +
**[[1rio]] - TaSF-A region 4 + repression protein CI + DNA<br />
 +
**[[5uha]], [[5uh5]], [[5uh8]], [[5uh9]], [[7u22]] – MtSF-A in transcription initiation complex<br />
 +
**[[6dcf]] – MtSF-A in transcription initiation complex + RbpA<br />
 +
**[[8hih]] – MtSF-A in transcription initiation complex + transctriptional regulatory protein – Cryo EM<br />
 +
**[[6c04]], [[7kin]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA - Cryo EM<br />
 +
**[[7kif]], [[7kim]] – MtSF-A + RNAP subunits α,β,β’,ω + WhiB7 + DNA - Cryo EM<br />
 +
**[[5uhe]], [[5uhf]] – MtSF-A in transcription initiation complex + inhibitor<br />
 +
**[[6jcy]], [[6jcx]], [[5zx2]] – MtSF-H in transcription initiation complex<br />
 +
**[[6kon]], [[6koo]], [[6kop]], [[6koq]] – MtSF-H in transcription initiation complex <br />
 +
**[[6dve]], [[6dvd]], [[7rwi]] – MtSF-L in transcription initiation complex<br />
 +
**[[6dvc]], [[6dvb]], [[6dv9]], [[6tye]], [[6tyf]], [[6tyg]] – MtSF-L in transcription initiation complex <br />
 +
**[[5tw1]], [[6cce]] – MsSF-A in transcription initiation complex + peptide - ''Mycobacterium smegmatis''<br />
 +
**[[5vi5]], [[5vi8]], [[6vvv]] – MsSF-A in transcription initiation complex<br />
 +
**[[7p5x]] – MsSF-A in transcription initiation complex + PafBC – Cryo EM<br />
 +
**[[8i24]] – AtSF-I6 + RNAP subunits α,β,β’,ω + DNA – ''Acetivibrio thermocellum'' - Cryo EM<br />
 +
**[[8i23]] – AtSF-I1 + RNAP subunits α,β,β’,ω + DNA - Cryo EM<br />
 +
**[[7ye1]] , [[7ye2]] – CcSF-70 + RNAP subunits α,β,β’,ω + DNA + GcrA – Cryo EM<br />
 +
**[[7f0r]] – PaSF-38 in transcription activation complex + SutA – Cryo EM<br />
 +
**[[7xl3]], [[7xl4]] – PaSF-S in transcription activation complex + SutA – Cryo EM<br />
 +
**[[7xya]] – PaSF-70 in transcription antitermination complex + ALPA – Cryo EM<br />
 +
**[[8gzg]], [[8gzh]] – SF-A + RNAP subunits α,β,β’,ω + DNA + RNA – ''Synechocystis'' - Cryo EM<br />
 +
**[[8h40]] – AnSF-A + RNAP subunits α,β,β’,ω + DNA + NtcA – ''Anabaena'' - Cryo EM<br />
 +
**[[8h3v]] – AnSF-A + RNAP subunits α,β,β’,ω + DNA + NtcA + NtcB - Cryo EM<br />
 +
**[[7vpd]], [[7vpz]], [[7x74]], [[7x75]], [[7x76]] – ScSF-A + RNAP subunits α,β,β’,ω + metal uptake regulation protein + DNA + RNA - Cryo EM<br />
 +
**[[68hkc]] – EcSF-32 in transcription initiation complex – Cryo EM<br />
 +
**[[6pmi]], [[6pmj]] – EcSF-28 in transcription initiation complex – Cryo EM<br />
 +
**[[5ipl]], [[5ipm]], [[5ipn]] – EcSF-38 in transcription initiation complex <br />
 +
**[[8dy7]], [[8dy9]] – SvSF-A + RNAP subunits α,β,β’,ω + WhiA + WhiB + RbpA + DNA - Cryo EM<br />
 +
 
*Sigma factor complex with protein and DNA and antibiotics
*Sigma factor complex with protein and DNA and antibiotics
-
**[[4oin]], [[4oip]], [[4oiq]], [[4oir]] – TtSF-A + RNAP subunits α,β,β’,ω + antibiotic + DNA<br />
+
**[[4oin]], [[4oip]], [[4oiq]], [[4oir]], [[5x21]] – TtSF-A in transcription initiation complex + antibiotic <br />
**[[6cuu]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + antibiotic<br />
**[[6cuu]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + antibiotic<br />
-
**[[5uhg]] – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + antibiotic + inhibitor<br />
+
**[[2a68]], [[2a69]], [[2a6h]], [[3dxj]], [[3eql]], [[4mq9]] – TtSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
-
**[[5uhb]] – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + antibiotic<br />
+
**[[5uhg]] – MtSF-A in transcription initiation complex + antibiotic + inhibitor<br />
-
**[[6bzo]] – MtSF-A + RNAP subunits α,β,β’,ω + RbpA + DNA + antibiotic - Cryo EM<br />
+
**[[5uh6]], [[5uhc]], [[5uhd]], [[5uhb]] – MtSF-A in transcription initiation complex + antibiotic<br />
-
**[[6ccf]] – MsSF-A + MtRNAP subunits α,β,β’,ω + DNA + peptide + antibiotic<br />
+
**[[6bzo]] – MtSF-A in transcription initiation complex + RbpA + antibiotic - Cryo EM<br />
-
 
+
**[[6vvt]], [[6vvx]], [[6vvz]] – MtSF-A in transcription initiation complex + antibiotic – Cryo EM<br />
-
*Sigma factor complex with protein, DNA and RNA
+
**[[6vvy]], [[6vw0]] – MtSF-A in transcription open promoter complex + antibiotic – Cryo EM<br />
 +
**[[6m7j]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + DNA + antibiotic – Cryo EM<br />
 +
**[[6eec]], [[6ee8]], [[6edt]] – MtSF-A + RNAP subunits α,β,β’,ω + RBPA + CARD + DNA + antibiotic – Cryo EM<br />
 +
**[[6ccv]] – MsSF-A in transcription initiation complex + peptide + RbpA + antibiotic<br />
 +
**[[7l7b]] – SF-A + RNAP subunits α,β,β’,ω + antibiotic – Clostridia bacterium - Cryo EM<br />
 +
**[[4mex]], [[4kmu]], [[4kn4]], [[4kn7]], [[4xsx]], [[4xsy]], [[4xsz]] [[4zh3]], [[4zh4]], [[5uac]], [[5uah]], [[5ual]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic <br />
 +
**[[7szj]] – EcSF-70 + RNAP subunits α,β,β’,ω + antibiotic – Cryo EM<br />
-
**[[5vi5]] – MsSF-A + MsRNAP subunits α,β,β’,ω + RbpA + DNA + RNA<br />
 
-
**[[4xln]] – TaSF-A + RNAP subunits α,β,β’,ω + DNA + RNA <br />
 
-
**[[5ipl]], [[5ipm]], [[5ipn]] – EcSF RpoS + EcRNAP subunits α,β,β’,ω + DNA + RNA<br />
 
-
**[[6b6h]] – EcSF RpoD + EcRNAP subunits α,β,β’,ω + DNA + RNA - Cryo EM<br />
 
-
**[[5e17]], [[5e18]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA<br />
 
-
**[[5x22]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + CMPPP<br />
 
-
**[[5vo8]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + GTP<br />
 
-
**[[5x21]] – TtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + antibiotic<br />
 
-
**[[5i2d]] – TtSF-A + TtRNAP subunits α,β,β’,ω + transcriptional regulator + DNA + RNA<br />
 
-
**[[5uh5]], [[5uh8]], [[5uh9]] – MtSF-A + MtRNAP subunits α,β,β’,ω + DNA + RNA<br />
 
-
**[[5uh6]], [[5uhc]], [[5uhd]], [[5x21]] – MtSF-A + TtRNAP subunits α,β,β’,ω + DNA + RNA + antibiotic<br />
 
}}
}}
[[Category:Topic Page]]
[[Category:Topic Page]]

Current revision

3D structures of sigma factor

Updated on 16-December-2023 

transcription complex


Proteopedia Page Contributors and Editors (what is this?)

Michal Harel, Joel L. Sussman, Jaime Prilusky

Retrieved from "http://52.214.119.220/wiki/index.php/Sigma_factor_3D_structures"
Personal tools