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8hn1
From Proteopedia
(Difference between revisions)
(New page: '''Unreleased structure''' The entry 8hn1 is ON HOLD Authors: Xiangyu, L., Mingyu, S. Description: Cryo-EM structure of AdTx1-alpha1AAR-Nb6 Category: Unreleased Structures [[Catego...) |
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| - | '''Unreleased structure''' | ||
| - | + | ==Cryo-EM structure of AdTx1-alpha1AAR-Nb6== | |
| - | + | <StructureSection load='8hn1' size='340' side='right'caption='[[8hn1]], [[Resolution|resolution]] 2.90Å' scene=''> | |
| - | + | == Structural highlights == | |
| - | + | <table><tr><td colspan='2'>[[8hn1]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Dendroaspis_angusticeps Dendroaspis angusticeps], [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens] and [https://en.wikipedia.org/wiki/Lama_glama Lama glama]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=8HN1 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=8HN1 FirstGlance]. <br> | |
| - | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Electron Microscopy, [[Resolution|Resolution]] 2.9Å</td></tr> | |
| - | [[Category: | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=8hn1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=8hn1 OCA], [https://pdbe.org/8hn1 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=8hn1 RCSB], [https://www.ebi.ac.uk/pdbsum/8hn1 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=8hn1 ProSAT]</span></td></tr> |
| - | [[Category: | + | </table> |
| - | [[Category: | + | == Function == |
| + | [https://www.uniprot.org/uniprot/ADA1A_HUMAN ADA1A_HUMAN] This alpha-adrenergic receptor mediates its action by association with G proteins that activate a phosphatidylinositol-calcium second messenger system. Its effect is mediated by G(q) and G(11) proteins. Nuclear ADRA1A-ADRA1B heterooligomers regulate phenylephrine(PE)-stimulated ERK signaling in cardiac myocytes.<ref>PMID:18802028</ref> <ref>PMID:22120526</ref> | ||
| + | == References == | ||
| + | <references/> | ||
| + | __TOC__ | ||
| + | </StructureSection> | ||
| + | [[Category: Dendroaspis angusticeps]] | ||
| + | [[Category: Homo sapiens]] | ||
| + | [[Category: Lama glama]] | ||
| + | [[Category: Large Structures]] | ||
| + | [[Category: Liu X]] | ||
| + | [[Category: Shi M]] | ||
Current revision
Cryo-EM structure of AdTx1-alpha1AAR-Nb6
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