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2jrf

From Proteopedia

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[[Image:2jrf.png|left|200px]]
 
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{{STRUCTURE_2jrf| PDB=2jrf | SCENE= }}
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==Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.==
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<StructureSection load='2jrf' size='340' side='right'caption='[[2jrf]]' scene=''>
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===Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[2jrf]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRF OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2JRF FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">Solution NMR</td></tr>
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==About this Structure==
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2jrf FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jrf OCA], [https://pdbe.org/2jrf PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2jrf RCSB], [https://www.ebi.ac.uk/pdbsum/2jrf PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2jrf ProSAT]</span></td></tr>
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[[2jrf]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2JRF OCA].
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/TPPP3_HUMAN TPPP3_HUMAN] Binds tubulin and has microtubule bundling activity. May play a role in cell proliferation and mitosis.<ref>PMID:17105200</ref> <ref>PMID:19633818</ref>
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/jr/2jrf_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2jrf ConSurf].
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<div style="clear:both"></div>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Acton, T B.]]
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[[Category: Large Structures]]
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[[Category: Aramini, J M.]]
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[[Category: Acton TB]]
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[[Category: Baran, M C.]]
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[[Category: Aramini JM]]
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[[Category: Cunningham, K.]]
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[[Category: Baran MC]]
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[[Category: Liu, J.]]
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[[Category: Cunningham K]]
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[[Category: Montelione, G T.]]
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[[Category: Liu J]]
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[[Category: NESG, Northeast Structural Genomics Consortium.]]
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[[Category: Montelione GT]]
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[[Category: Nwosu, C.]]
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[[Category: Nwosu C]]
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[[Category: Rajan, P K.]]
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[[Category: Rajan PK]]
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[[Category: Rossi, P.]]
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[[Category: Rossi P]]
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[[Category: Rost, B.]]
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[[Category: Rost B]]
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[[Category: Shastry, R.]]
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[[Category: Shastry R]]
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[[Category: Xiao, R.]]
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[[Category: Xiao R]]
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[[Category: Nesg]]
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[[Category: Northeast structural genomics consortium]]
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[[Category: Protein structure initiative]]
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[[Category: Psi-2]]
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[[Category: Solution nmr structure]]
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[[Category: Structural genomic]]
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[[Category: Unknown function]]
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Current revision

Solution NMR structure of Tubulin polymerization-promoting protein family member 3 from Homo sapiens. Northeast Structural Genomics target HR387.

PDB ID 2jrf

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