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2x3f

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<StructureSection load='2x3f' size='340' side='right'caption='[[2x3f]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
<StructureSection load='2x3f' size='340' side='right'caption='[[2x3f]], [[Resolution|resolution]] 1.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2x3f]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Staar Staar]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X3F OCA]. For a <b>guided tour on the structure components</b> use [http://proteopedia.org/fgij/fg.htm?mol=2X3F FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2x3f]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Staphylococcus_aureus_subsp._aureus_MRSA252 Staphylococcus aureus subsp. aureus MRSA252]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X3F OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X3F FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.95&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Pantoate--beta-alanine_ligase Pantoate--beta-alanine ligase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=6.3.2.1 6.3.2.1] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=APC:DIPHOSPHOMETHYLPHOSPHONIC+ACID+ADENOSYL+ESTER'>APC</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://proteopedia.org/fgij/fg.htm?mol=2x3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x3f OCA], [http://pdbe.org/2x3f PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x3f RCSB], [http://www.ebi.ac.uk/pdbsum/2x3f PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x3f ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x3f FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x3f OCA], [https://pdbe.org/2x3f PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x3f RCSB], [https://www.ebi.ac.uk/pdbsum/2x3f PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x3f ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/PANC_STAAR PANC_STAAR] Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate.[HAMAP-Rule:MF_00158]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Pantoate--beta-alanine ligase]]
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[[Category: Staphylococcus aureus subsp. aureus MRSA252]]
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[[Category: Staar]]
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[[Category: Carter LG]]
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[[Category: Carter, L G]]
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[[Category: Johnson KA]]
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[[Category: Johnson, K A]]
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[[Category: Liu H]]
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[[Category: Liu, H]]
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[[Category: Mcmahon SA]]
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[[Category: Mcmahon, S A]]
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[[Category: Naismith JH]]
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[[Category: Naismith, J H]]
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[[Category: Oke M]]
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[[Category: Oke, M]]
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[[Category: White MF]]
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[[Category: White, M F]]
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[[Category: Atp-binding]]
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[[Category: Ligase]]
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[[Category: Nucleotide-binding]]
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[[Category: Pantothenate biosynthesis]]
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Current revision

Crystal Structure of the Methicillin-Resistant Staphylococcus aureus Sar2676, a Pantothenate Synthetase.

PDB ID 2x3f

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