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2x6j
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==THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-93== | ==THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-93== | ||
| - | <StructureSection load='2x6j' size='340' side='right' caption='[[2x6j]], [[Resolution|resolution]] 3.50Å' scene=''> | + | <StructureSection load='2x6j' size='340' side='right'caption='[[2x6j]], [[Resolution|resolution]] 3.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2x6j]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2x6j]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Drosophila_melanogaster Drosophila melanogaster]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X6J OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X6J FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 3.5Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=093:N-(5-(4-CHLORO-3-(2-HYDROXY-ETHYLSULFAMOYL)-+PHENYLTHIAZOLE-2-YL)-ACETAMIDE'>093</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x6j FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x6j OCA], [https://pdbe.org/2x6j PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x6j RCSB], [https://www.ebi.ac.uk/pdbsum/2x6j PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x6j ProSAT]</span></td></tr> |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/Q9W1M7_DROME Q9W1M7_DROME] | ||
== Evolutionary Conservation == | == Evolutionary Conservation == | ||
[[Image:Consurf_key_small.gif|200px|right]] | [[Image:Consurf_key_small.gif|200px|right]] | ||
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</div> | </div> | ||
<div class="pdbe-citations 2x6j" style="background-color:#fffaf0;"></div> | <div class="pdbe-citations 2x6j" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[Phosphoinositide 3-kinase 3D structures|Phosphoinositide 3-kinase 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Drosophila melanogaster]] |
| - | [[Category: Houseman | + | [[Category: Large Structures]] |
| - | [[Category: Miller | + | [[Category: Houseman BT]] |
| - | [[Category: Oleksy | + | [[Category: Miller S]] |
| - | [[Category: Perisic | + | [[Category: Oleksy A]] |
| - | [[Category: Shokat | + | [[Category: Perisic O]] |
| - | [[Category: Tavshanjian | + | [[Category: Shokat KM]] |
| - | [[Category: Williams | + | [[Category: Tavshanjian B]] |
| - | + | [[Category: Williams RL]] | |
Current revision
THE CRYSTAL STRUCTURE OF THE DROSOPHILA CLASS III PI3-KINASE VPS34 IN COMPLEX WITH PIK-93
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