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2x9m

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==HENDRA VIRUS ATTACHMENT GLYCOPROTEIN==
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==Hendra virus attachment glycoprotein==
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<StructureSection load='2x9m' size='340' side='right' caption='[[2x9m]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
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<StructureSection load='2x9m' size='340' side='right'caption='[[2x9m]], [[Resolution|resolution]] 2.90&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2x9m]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Equine_morbillivirus Equine morbillivirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9M OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2X9M FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2x9m]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Hendra_henipavirus Hendra henipavirus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2X9M OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2X9M FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.9&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vsk|2vsk]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2x9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x9m OCA], [http://pdbe.org/2x9m PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2x9m RCSB], [http://www.ebi.ac.uk/pdbsum/2x9m PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2x9m ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2x9m FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2x9m OCA], [https://pdbe.org/2x9m PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2x9m RCSB], [https://www.ebi.ac.uk/pdbsum/2x9m PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2x9m ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/GLYCP_HENDH GLYCP_HENDH]] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of glycoprotein G to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).
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[https://www.uniprot.org/uniprot/GLYCP_HENDH GLYCP_HENDH] Attaches the virus to sialic acid-containing cell receptors and thereby initiating infection. Binding of glycoprotein G to the receptor induces a conformational change that allows the F protein to trigger virion/cell membranes fusion (By similarity).
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x9/2x9m_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/x9/2x9m_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Equine morbillivirus]]
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[[Category: Hendra henipavirus]]
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[[Category: Bowden, T A]]
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[[Category: Large Structures]]
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[[Category: Crispin, M]]
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[[Category: Bowden TA]]
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[[Category: Harvey, D]]
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[[Category: Crispin M]]
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[[Category: Jones, E Y]]
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[[Category: Harvey D]]
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[[Category: Stuart, D I]]
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[[Category: Jones EY]]
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[[Category: Efnb2]]
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[[Category: Stuart DI]]
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[[Category: Efnb3]]
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[[Category: Ephrinb2]]
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[[Category: Ephrinb3]]
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[[Category: Henipavirus]]
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[[Category: Hnv]]
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[[Category: Nipah virus]]
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[[Category: Niv-g]]
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[[Category: Paramyxovirus]]
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[[Category: Viral attachment]]
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[[Category: Viral protein]]
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[[Category: Viral surface]]
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[[Category: Virus envelope]]
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Current revision

Hendra virus attachment glycoprotein

PDB ID 2x9m

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Proteopedia Page Contributors and Editors (what is this?)

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