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2xd5

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{{Seed}}
 
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[[Image:2xd5.jpg|left|200px]]
 
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==Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b==
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The line below this paragraph, containing "STRUCTURE_2xd5", creates the "Structure Box" on the page.
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<StructureSection load='2xd5' size='340' side='right'caption='[[2xd5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2xd5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jci 2jci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD5 FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=S2D:N-BENZOYL-D-ALANINE'>S2D</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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{{STRUCTURE_2xd5| PDB=2xd5 | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd5 OCA], [https://pdbe.org/2xd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd5 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd5 ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q7CRA4_STRR6 Q7CRA4_STRR6]
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== Evolutionary Conservation ==
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[[Image:Consurf_key_small.gif|200px|right]]
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Check<jmol>
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<jmolCheckbox>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd5_consurf.spt"</scriptWhenChecked>
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<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
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<text>to colour the structure by Evolutionary Conservation</text>
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</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xd5 ConSurf].
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<div style="clear:both"></div>
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===STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM AND THE ROLE OF STREPTOCOCCUS PNEUMONIAE PBP1B===
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==See Also==
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*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
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__TOC__
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==About this Structure==
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</StructureSection>
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2XD5 is a 2 chains structure with sequences from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jci 2jci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD5 OCA].
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[[Category: Large Structures]]
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[[Category: Streptococcus pneumoniae R6]]
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==Reference==
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[[Category: Dessen A]]
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<ref group="xtra">PMID:18155726</ref><references group="xtra"/>
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[[Category: Dideberg O]]
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[[Category: Streptococcus pneumoniae]]
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[[Category: Jamin M]]
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[[Category: Dessen, A.]]
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[[Category: Lemaire D]]
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[[Category: Dideberg, O.]]
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[[Category: Macheboeuf P]]
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[[Category: Jamin, M.]]
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[[Category: Lemaire, D.]]
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[[Category: Macheboeuf, P.]]
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[[Category: Cell wall]]
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[[Category: Multifunctional enzyme]]
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[[Category: Peptidoglycan synthesis]]
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[[Category: Pseudo-substrate]]
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[[Category: Transferase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 26 08:26:40 2010''
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Current revision

Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b

PDB ID 2xd5

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