This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


2xd5

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
m (Protected "2xd5" [edit=sysop:move=sysop])
Current revision (10:29, 20 December 2023) (edit) (undo)
 
(7 intermediate revisions not shown.)
Line 1: Line 1:
-
[[Image:2xd5.png|left|200px]]
 
-
{{STRUCTURE_2xd5| PDB=2xd5 | SCENE= }}
+
==Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b==
-
 
+
<StructureSection load='2xd5' size='340' side='right'caption='[[2xd5]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
-
===STRUCTURAL INSIGHTS INTO THE CATALYTIC MECHANISM AND THE ROLE OF STREPTOCOCCUS PNEUMONIAE PBP1B===
+
== Structural highlights ==
-
 
+
<table><tr><td colspan='2'>[[2xd5]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Streptococcus_pneumoniae_R6 Streptococcus pneumoniae R6]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jci 2jci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD5 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XD5 FirstGlance]. <br>
-
{{ABSTRACT_PUBMED_18155726}}
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
 
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=S2D:N-BENZOYL-D-ALANINE'>S2D</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
==About this Structure==
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xd5 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xd5 OCA], [https://pdbe.org/2xd5 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xd5 RCSB], [https://www.ebi.ac.uk/pdbsum/2xd5 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xd5 ProSAT]</span></td></tr>
-
[[2xd5]] is a 2 chain structure of [[Penicillin-binding protein]] with sequence from [http://en.wikipedia.org/wiki/Streptococcus_pneumoniae Streptococcus pneumoniae]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2jci 2jci]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XD5 OCA].
+
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/Q7CRA4_STRR6 Q7CRA4_STRR6]
 +
== Evolutionary Conservation ==
 +
[[Image:Consurf_key_small.gif|200px|right]]
 +
Check<jmol>
 +
<jmolCheckbox>
 +
<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xd/2xd5_consurf.spt"</scriptWhenChecked>
 +
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
 +
<text>to colour the structure by Evolutionary Conservation</text>
 +
</jmolCheckbox>
 +
</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xd5 ConSurf].
 +
<div style="clear:both"></div>
==See Also==
==See Also==
-
*[[Penicillin-binding protein|Penicillin-binding protein]]
+
*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
-
 
+
__TOC__
-
==Reference==
+
</StructureSection>
-
<ref group="xtra">PMID:018155726</ref><references group="xtra"/>
+
[[Category: Large Structures]]
-
[[Category: Streptococcus pneumoniae]]
+
[[Category: Streptococcus pneumoniae R6]]
-
[[Category: Dessen, A.]]
+
[[Category: Dessen A]]
-
[[Category: Dideberg, O.]]
+
[[Category: Dideberg O]]
-
[[Category: Jamin, M.]]
+
[[Category: Jamin M]]
-
[[Category: Lemaire, D.]]
+
[[Category: Lemaire D]]
-
[[Category: Macheboeuf, P.]]
+
[[Category: Macheboeuf P]]
-
[[Category: Cell wall]]
+
-
[[Category: Multifunctional enzyme]]
+
-
[[Category: Peptidoglycan synthesis]]
+
-
[[Category: Pseudo-substrate]]
+
-
[[Category: Transferase]]
+

Current revision

Structural insights into the catalytic mechanism and the role of Streptococcus pneumoniae PBP1b

PDB ID 2xd5

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2xd5"
Personal tools