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2xf8

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==STRUCTURE OF THE D-ERYTHROSE-4-PHOSPHATE DEHYDROGENASE FROM E.COLI IN COMPLEX WITH A NAD COFACTOR ANALOG (3-CHLOROACETYL ADENINE PYRIDINE DINUCLEOTIDE) AND SULFATE ANION==
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==Structure of the D-Erythrose-4-Phosphate Dehydrogenase from E. coli in complex with a NAD cofactor analog (3-Chloroacetyl adenine pyridine dinucleotide) and sulfate anion==
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<StructureSection load='2xf8' size='340' side='right' caption='[[2xf8]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
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<StructureSection load='2xf8' size='340' side='right'caption='[[2xf8]], [[Resolution|resolution]] 2.95&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xf8]] is a 16 chain structure with sequence from [http://en.wikipedia.org/wiki/Ecoli Ecoli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XF8 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2XF8 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xf8]] is a 16 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_K-12 Escherichia coli K-12]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XF8 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XF8 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=3CD:3-(CHLOROACETYL)+PYRIDINE+ADENINE+DINUCLEOTIDE'>3CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.95&#8491;</td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Erythrose-4-phosphate_dehydrogenase Erythrose-4-phosphate dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.2.1.72 1.2.1.72] </span></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=3CD:3-(CHLOROACETYL)+PYRIDINE+ADENINE+DINUCLEOTIDE'>3CD</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xf8 OCA], [http://pdbe.org/2xf8 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2xf8 RCSB], [http://www.ebi.ac.uk/pdbsum/2xf8 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2xf8 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xf8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xf8 OCA], [https://pdbe.org/2xf8 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xf8 RCSB], [https://www.ebi.ac.uk/pdbsum/2xf8 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xf8 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/E4PD_ECOLI E4PD_ECOLI]] Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.<ref>PMID:9182530</ref> <ref>PMID:9696782</ref>
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[https://www.uniprot.org/uniprot/E4PD_ECOLI E4PD_ECOLI] Catalyzes the NAD-dependent conversion of D-erythrose 4-phosphate to 4-phosphoerythronate.<ref>PMID:9182530</ref> <ref>PMID:9696782</ref>
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Ecoli]]
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[[Category: Escherichia coli K-12]]
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[[Category: Erythrose-4-phosphate dehydrogenase]]
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[[Category: Large Structures]]
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[[Category: Boschi-Muller, S]]
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[[Category: Boschi-Muller S]]
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[[Category: Branlant, G]]
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[[Category: Branlant G]]
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[[Category: Corbier, C]]
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[[Category: Corbier C]]
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[[Category: Didierjean, C]]
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[[Category: Didierjean C]]
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[[Category: Moniot, S]]
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[[Category: Moniot S]]
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[[Category: Aldehyde dehydrogenase]]
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[[Category: Cofactor analog]]
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[[Category: Hydride transfer]]
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[[Category: Oxidoreductase]]
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[[Category: Pyridoxal phophate biosynthesis]]
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Current revision

Structure of the D-Erythrose-4-Phosphate Dehydrogenase from E. coli in complex with a NAD cofactor analog (3-Chloroacetyl adenine pyridine dinucleotide) and sulfate anion

PDB ID 2xf8

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