2xgo

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==XCOGT IN COMPLEX WITH UDP-S-GLCNAC==
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<StructureSection load='2xgo' size='340' side='right' caption='[[2xgo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
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==XcOGT in complex with UDP-S-GlcNAc==
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<StructureSection load='2xgo' size='340' side='right'caption='[[2xgo]], [[Resolution|resolution]] 2.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xgo]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Xanthomonas_campestris Xanthomonas campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XGO OCA]. <br>
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<table><tr><td colspan='2'>[[2xgo]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Xanthomonas_campestris Xanthomonas campestris]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XGO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XGO FirstGlance]. <br>
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</td></tr><tr><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ZKD:URIDINE-DIPHOSPHATE-1-DEOXY-1-THIO-N-ACETYLGLUCOSAMINE'>ZKD</scene><br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.6&#8491;</td></tr>
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<tr><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2vsy|2vsy]], [[2jlb|2jlb]], [[2xgs|2xgs]], [[2xgm|2xgm]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ZKD:URIDINE-DIPHOSPHATE-1-DEOXY-1-THIO-N-ACETYLGLUCOSAMINE'>ZKD</scene></td></tr>
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<tr><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Glucokinase Glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.2 2.7.1.2] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xgo OCA], [https://pdbe.org/2xgo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xgo RCSB], [https://www.ebi.ac.uk/pdbsum/2xgo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xgo ProSAT]</span></td></tr>
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<tr><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2xgo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xgo OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2xgo RCSB], [http://www.ebi.ac.uk/pdbsum/2xgo PDBsum]</span></td></tr>
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</table>
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<table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8PC69_XANCP Q8PC69_XANCP]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
Check<jmol>
Check<jmol>
<jmolCheckbox>
<jmolCheckbox>
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<scriptWhenChecked>select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/2xgo_consurf.spt"</scriptWhenChecked>
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<scriptWhenChecked>; select protein; define ~consurf_to_do selected; consurf_initial_scene = true; script "/wiki/ConSurf/xg/2xgo_consurf.spt"</scriptWhenChecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<scriptWhenUnchecked>script /wiki/extensions/Proteopedia/spt/initialview01.spt</scriptWhenUnchecked>
<text>to colour the structure by Evolutionary Conservation</text>
<text>to colour the structure by Evolutionary Conservation</text>
</jmolCheckbox>
</jmolCheckbox>
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/chain_selection.php?pdb_ID=2ata ConSurf].
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</jmol>, as determined by [http://consurfdb.tau.ac.il/ ConSurfDB]. You may read the [[Conservation%2C_Evolutionary|explanation]] of the method and the full data available from [http://bental.tau.ac.il/new_ConSurfDB/main_output.php?pdb_ID=2xgo ConSurf].
<div style="clear:both"></div>
<div style="clear:both"></div>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
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Substrate and product analogues as human O-GlcNAc transferase inhibitors.,Dorfmueller HC, Borodkin VS, Blair DE, Pathak S, Navratilova I, van Aalten DM Amino Acids. 2010 Jul 17. PMID:20640461<ref>PMID:20640461</ref>
Substrate and product analogues as human O-GlcNAc transferase inhibitors.,Dorfmueller HC, Borodkin VS, Blair DE, Pathak S, Navratilova I, van Aalten DM Amino Acids. 2010 Jul 17. PMID:20640461<ref>PMID:20640461</ref>
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br>
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2xgo" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[O-GlcNAc transferase 3D structures|O-GlcNAc transferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Xanthomonas campestris]]
[[Category: Xanthomonas campestris]]
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[[Category: Aalten, D M.Van.]]
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[[Category: Blair DE]]
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[[Category: Blair, D E.]]
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[[Category: Borodkin VS]]
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[[Category: Borodkin, V S.]]
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[[Category: Dorfmueller HC]]
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[[Category: Dorfmueller, H C.]]
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[[Category: Navratilova I]]
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[[Category: Navratilova, I.]]
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[[Category: Pathak S]]
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[[Category: Pathak, S.]]
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[[Category: Van Aalten DM]]
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[[Category: Transferase]]
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Current revision

XcOGT in complex with UDP-S-GlcNAc

PDB ID 2xgo

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