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2xii

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Current revision (10:32, 20 December 2023) (edit) (undo)
 
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<StructureSection load='2xii' size='340' side='right'caption='[[2xii]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
<StructureSection load='2xii' size='340' side='right'caption='[[2xii]], [[Resolution|resolution]] 1.80&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2xii]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"bacillus_thetaiotaomicron"_distaso_1912 "bacillus thetaiotaomicron" distaso 1912]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XII FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2xii]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Bacteroides_thetaiotaomicron Bacteroides thetaiotaomicron]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XII OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XII FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TA9:9-OXO-N-[[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-PIPERIDIN-2-YL]METHYL]FLUORENE-1-CARBOXAMIDE'>TA9</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.8&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2wvt|2wvt]], [[2wvs|2wvs]], [[2wvu|2wvu]], [[2wvv|2wvv]], [[2xib|2xib]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>, <scene name='pdbligand=TA9:9-OXO-N-[[(2R,3R,4R,5R,6S)-3,4,5-TRIHYDROXY-6-METHYL-PIPERIDIN-2-YL]METHYL]FLUORENE-1-CARBOXAMIDE'>TA9</scene>, <scene name='pdbligand=TYR:TYROSINE'>TYR</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Alpha-L-fucosidase Alpha-L-fucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.51 3.2.1.51] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xii OCA], [https://pdbe.org/2xii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xii RCSB], [https://www.ebi.ac.uk/pdbsum/2xii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xii ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xii FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xii OCA], [https://pdbe.org/2xii PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xii RCSB], [https://www.ebi.ac.uk/pdbsum/2xii PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xii ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8A3I4_BACTN Q8A3I4_BACTN]
== Evolutionary Conservation ==
== Evolutionary Conservation ==
[[Image:Consurf_key_small.gif|200px|right]]
[[Image:Consurf_key_small.gif|200px|right]]
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Bacillus thetaiotaomicron distaso 1912]]
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[[Category: Bacteroides thetaiotaomicron]]
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[[Category: Alpha-L-fucosidase]]
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[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Bueren, A Lammerts van]]
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[[Category: Davies GJ]]
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[[Category: Davies, G J]]
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[[Category: Lammerts van Bueren A]]
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[[Category: Lin, C H]]
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[[Category: Lin CH]]
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[[Category: Popat, S D]]
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[[Category: Popat SD]]
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[[Category: Fucose]]
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[[Category: Hydrolase]]
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Current revision

CRYSTAL STRUCTURE OF AN ALPHA-L-FUCOSIDASE GH29 FROM BACTEROIDES THETAIOTAOMICRON IN COMPLEX WITH AN EXTENDED 9-FLUORENONE IMINOSUGAR INHIBITOR

PDB ID 2xii

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