This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
2xva
From Proteopedia
(Difference between revisions)
| (2 intermediate revisions not shown.) | |||
| Line 1: | Line 1: | ||
==Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin== | ==Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin== | ||
| - | <StructureSection load='2xva' size='340' side='right' caption='[[2xva]], [[Resolution|resolution]] 1.90Å' scene=''> | + | <StructureSection load='2xva' size='340' side='right'caption='[[2xva]], [[Resolution|resolution]] 1.90Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2xva]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2xva]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Escherichia_coli_str._K-12_substr._MG1655 Escherichia coli str. K-12 substr. MG1655]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2XVA OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2XVA FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.9Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=SFG:SINEFUNGIN'>SFG</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2xva FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2xva OCA], [https://pdbe.org/2xva PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2xva RCSB], [https://www.ebi.ac.uk/pdbsum/2xva PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2xva ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/TEHB_ECOLI TEHB_ECOLI] S-adenosyl-L-methionine dependent methyltransferase that catalyzes the methylation of tellurite and is responsible for tellurite resistance when present in high copy number. Can also methylate selenite and selenium dioxide. Is thus able to detoxify different chalcogens. Can not methylate arsenic compounds.<ref>PMID:11053398</ref> <ref>PMID:21244361</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
| Line 23: | Line 23: | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: Escherichia coli | + | [[Category: Escherichia coli str. K-12 substr. MG1655]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: | + | [[Category: Beis K]] |
| - | [[Category: | + | [[Category: Cameron AD]] |
| - | [[Category: | + | [[Category: Choudhury HG]] |
| - | [[Category: | + | [[Category: Iwata S]] |
Current revision
Crystal structure of the tellurite detoxification protein TehB from E. coli in complex with sinefungin
| |||||||||||
