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2y6w
From Proteopedia
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| - | == | + | |
| - | <StructureSection load='2y6w' size='340' side='right' caption='[[2y6w]], [[Resolution|resolution]] 2.00Å' scene=''> | + | ==Structure of a Bcl-w dimer== |
| + | <StructureSection load='2y6w' size='340' side='right'caption='[[2y6w]], [[Resolution|resolution]] 2.00Å' scene=''> | ||
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[2y6w]] is a 2 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[2y6w]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y6W OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y6W FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y6w FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y6w OCA], [https://pdbe.org/2y6w PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y6w RCSB], [https://www.ebi.ac.uk/pdbsum/2y6w PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y6w ProSAT]</span></td></tr> |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/B2CL2_HUMAN B2CL2_HUMAN] Promotes cell survival. Blocks dexamethasone-induced apoptosis. Mediates survival of postmitotic Sertoli cells by suppressing death-promoting activity of BAX.<ref>PMID:8761287</ref> |
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 2y6w" style="background-color:#fffaf0;"></div> | ||
| + | |||
| + | ==See Also== | ||
| + | *[[B-cell lymphoma proteins 3D structures|B-cell lymphoma proteins 3D structures]] | ||
== References == | == References == | ||
<references/> | <references/> | ||
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</StructureSection> | </StructureSection> | ||
[[Category: Homo sapiens]] | [[Category: Homo sapiens]] | ||
| - | [[Category: Colman | + | [[Category: Large Structures]] |
| - | [[Category: Dogovski | + | [[Category: Colman PM]] |
| - | [[Category: Evangelista | + | [[Category: Dogovski C]] |
| - | [[Category: Fairlie | + | [[Category: Evangelista M]] |
| - | [[Category: Lee | + | [[Category: Fairlie WD]] |
| - | [[Category: Perugini | + | [[Category: Lee EF]] |
| - | [[Category: Pettikiriarachchi | + | [[Category: Perugini MA]] |
| - | + | [[Category: Pettikiriarachchi A]] | |
Current revision
Structure of a Bcl-w dimer
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