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2y7l

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==STRUCTURE OF N-TERMINAL DOMAIN OF CANDIDA ALBICANS ALS9-2 IN COMPLEX WITH HUMAN FIBRINOGEN GAMMA PEPTIDE==
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==Structure of N-terminal domain of Candida albicans Als9-2 in complex with human fibrinogen gamma peptide==
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<StructureSection load='2y7l' size='340' side='right' caption='[[2y7l]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
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<StructureSection load='2y7l' size='340' side='right'caption='[[2y7l]], [[Resolution|resolution]] 1.49&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y7l]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Atcc_11006_[[candida_stellatoidea]] Atcc 11006 [[candida stellatoidea]]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7L OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y7L FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2y7l]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Candida_albicans Candida albicans] and [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y7L OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y7L FirstGlance]. <br>
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</td></tr><tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2y7n|2y7n]], [[2y7m|2y7m]], [[2y7o|2y7o]]</td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.49&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7l OCA], [http://pdbe.org/2y7l PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2y7l RCSB], [http://www.ebi.ac.uk/pdbsum/2y7l PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7l ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y7l FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y7l OCA], [https://pdbe.org/2y7l PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y7l RCSB], [https://www.ebi.ac.uk/pdbsum/2y7l PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y7l ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/ALS9_CANAL ALS9_CANAL] Cell surface adhesion protein which mediates both yeast-to-host tissue adherence and yeast aggregation. Plays an important role in the pathogenesis of C.albicans infections (PubMed:17510860, PubMed:22321066, PubMed:22429754). Allele ALS9-2 contributes to endothelial cell adhesion, whereas ALS9-1 does not (PubMed:17600078).<ref>PMID:17510860</ref> <ref>PMID:17600078</ref> <ref>PMID:22321066</ref> <ref>PMID:22429754</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Cota, E]]
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[[Category: Candida albicans]]
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[[Category: Salgado, P S]]
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[[Category: Homo sapiens]]
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[[Category: Adhesin]]
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[[Category: Large Structures]]
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[[Category: Cell adhesion]]
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[[Category: Cota E]]
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[[Category: Peptide binding protein]]
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[[Category: Salgado PS]]

Current revision

Structure of N-terminal domain of Candida albicans Als9-2 in complex with human fibrinogen gamma peptide

PDB ID 2y7l

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