2y8c

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==Plasmodium falciparum dUTPase in complex with a trityl ligand==
==Plasmodium falciparum dUTPase in complex with a trityl ligand==
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<StructureSection load='2y8c' size='340' side='right' caption='[[2y8c]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
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<StructureSection load='2y8c' size='340' side='right'caption='[[2y8c]], [[Resolution|resolution]] 2.10&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2y8c]] is a 3 chain structure with sequence from [http://en.wikipedia.org/wiki/Plasmodium_falciparum Plasmodium falciparum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y8C OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2Y8C FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2y8c]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_falciparum_3D7 Plasmodium falciparum 3D7]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2Y8C OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2Y8C FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=DUQ:(2S)-2-[(2,4-DIOXOPYRIMIDIN-1-YL)METHYL]-N-(2-HYDROXYETHYL)-4-TRITYLOXY-BUTANAMIDE'>DUQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.1&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1vyq|1vyq]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=DUQ:(2S)-2-[(2,4-DIOXOPYRIMIDIN-1-YL)METHYL]-N-(2-HYDROXYETHYL)-4-TRITYLOXY-BUTANAMIDE'>DUQ</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/dUTP_diphosphatase dUTP diphosphatase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.1.23 3.6.1.23] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2y8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y8c OCA], [https://pdbe.org/2y8c PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2y8c RCSB], [https://www.ebi.ac.uk/pdbsum/2y8c PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2y8c ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2y8c FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2y8c OCA], [http://www.rcsb.org/pdb/explore.do?structureId=2y8c RCSB], [http://www.ebi.ac.uk/pdbsum/2y8c PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/Q8II92_PLAF7 Q8II92_PLAF7]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 2y8c" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Deoxyuridine 5'-triphosphate nucleotidohydrolase|Deoxyuridine 5'-triphosphate nucleotidohydrolase]]
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*[[DUTPase 3D structures|DUTPase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Plasmodium falciparum]]
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[[Category: Large Structures]]
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[[Category: DUTP diphosphatase]]
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[[Category: Plasmodium falciparum 3D7]]
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[[Category: Baragana, B]]
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[[Category: Baragana B]]
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[[Category: Bosch, C]]
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[[Category: Bosch C]]
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[[Category: Brun, R]]
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[[Category: Brun R]]
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[[Category: Gilbert, I H]]
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[[Category: Gilbert IH]]
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[[Category: Gonzalez-Pacanowska, D]]
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[[Category: Gonzalez-Pacanowska D]]
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[[Category: Johansson, N G]]
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[[Category: Johansson NG]]
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[[Category: Kaiser, M]]
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[[Category: Kaiser M]]
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[[Category: Mccarthy, O]]
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[[Category: McCarthy O]]
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[[Category: Roberts, S]]
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[[Category: Roberts S]]
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[[Category: Sanchez, P]]
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[[Category: Sanchez P]]
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[[Category: Whittingham, J L]]
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[[Category: Whittingham JL]]
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[[Category: Wilson, K S]]
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[[Category: Wilson KS]]
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[[Category: Zhou, X X]]
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[[Category: Zhou X-X]]
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[[Category: Hydrolase]]
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[[Category: Malaria]]
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Current revision

Plasmodium falciparum dUTPase in complex with a trityl ligand

PDB ID 2y8c

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