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2yeo

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Current revision (10:51, 20 December 2023) (edit) (undo)
 
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[[Image:2yeo.png|left|200px]]
 
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==A39L mutation of scorpion toxin lqh-alpha-it==
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The line below this paragraph, containing "STRUCTURE_2yeo", creates the "Structure Box" on the page.
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<StructureSection load='2yeo' size='340' side='right'caption='[[2yeo]], [[Resolution|resolution]] 1.08&Aring;' scene=''>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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== Structural highlights ==
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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<table><tr><td colspan='2'>[[2yeo]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Leiurus_quinquestriatus_hebraeus Leiurus quinquestriatus hebraeus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YEO OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YEO FirstGlance]. <br>
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or leave the SCENE parameter empty for the default display.
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.08&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DR0:N-(HYDROXYMETHYL)-N,N-DIMETHYLHEXAN-1-AMINIUM'>DR0</scene>, <scene name='pdbligand=DR8:N,N,N-TRIMETHYLHEPTA-1,3,5-TRIYN-1-AMINIUM'>DR8</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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{{STRUCTURE_2yeo| PDB=2yeo | SCENE= }}
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yeo FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yeo OCA], [https://pdbe.org/2yeo PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yeo RCSB], [https://www.ebi.ac.uk/pdbsum/2yeo PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yeo ProSAT]</span></td></tr>
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</table>
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===A39L MUTATION OF SCORPION TOXIN LQH-ALPHA-IT===
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== Function ==
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[https://www.uniprot.org/uniprot/SCXA_LEIHE SCXA_LEIHE] Alpha toxins bind voltage-independently at site-3 of sodium channels (Nav) and inhibit the inactivation of the activated channels, thereby blocking neuronal transmission. The dissociation is voltage-dependent. This toxin is active on insects. It is also highly toxic to crustaceans and has a measurable but low toxicity to mice.
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__TOC__
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==About this Structure==
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</StructureSection>
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[[2yeo]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Leiurus_quinquestriatus_hebraeus Leiurus quinquestriatus hebraeus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YEO OCA].
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[[Category: Large Structures]]
[[Category: Leiurus quinquestriatus hebraeus]]
[[Category: Leiurus quinquestriatus hebraeus]]
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[[Category: Frolow, F.]]
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[[Category: Frolow F]]
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[[Category: Gurevitz, M.]]
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[[Category: Gurevitz M]]
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[[Category: Kahn, R.]]
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[[Category: Kahn R]]

Current revision

A39L mutation of scorpion toxin lqh-alpha-it

PDB ID 2yeo

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