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2yk7

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==Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.==
==Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.==
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<StructureSection load='2yk7' size='340' side='right' caption='[[2yk7]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
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<StructureSection load='2yk7' size='340' side='right'caption='[[2yk7]], [[Resolution|resolution]] 2.18&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[2yk7]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Neimi Neimi]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK7 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2YK7 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[2yk7]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Neisseria_meningitidis_serogroup_B Neisseria meningitidis serogroup B]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2YK7 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=2YK7 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.18&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[2yk4|2yk4]], [[2yk5|2yk5]], [[2yk6|2yk6]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=1PE:PENTAETHYLENE+GLYCOL'>1PE</scene>, <scene name='pdbligand=CSF:CYTIDINE-5-MONOPHOSPHATE-3-FLUORO-N-ACETYL-NEURAMINIC+ACID'>CSF</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2yk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk7 OCA], [http://pdbe.org/2yk7 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=2yk7 RCSB], [http://www.ebi.ac.uk/pdbsum/2yk7 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=2yk7 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=2yk7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2yk7 OCA], [https://pdbe.org/2yk7 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=2yk7 RCSB], [https://www.ebi.ac.uk/pdbsum/2yk7 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=2yk7 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/LST_NEIMB LST_NEIMB]] Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide.
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[https://www.uniprot.org/uniprot/LST_NEIMB LST_NEIMB] Transfers sialic acid from the substrate CMP-sialic acid donor to the terminal beta-D-galactosyl-1,4-acetyl-beta-D-glucosamine on the lacto-N-neotetraose branch of the lipooligosaccharide.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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</div>
</div>
<div class="pdbe-citations 2yk7" style="background-color:#fffaf0;"></div>
<div class="pdbe-citations 2yk7" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Sialyltransferase 3D structures|Sialyltransferase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Neimi]]
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[[Category: Large Structures]]
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[[Category: Chiu, C P.C]]
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[[Category: Neisseria meningitidis serogroup B]]
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[[Category: Lameignere, E]]
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[[Category: Chiu CPC]]
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[[Category: Lin, L Y.C]]
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[[Category: Lameignere E]]
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[[Category: Rakic, B]]
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[[Category: Lin LYC]]
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[[Category: Strynadka, N C.J]]
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[[Category: Rakic B]]
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[[Category: Wakarchuk, W W]]
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[[Category: Strynadka NCJ]]
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[[Category: Withers, S G]]
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[[Category: Wakarchuk WW]]
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[[Category: Transferase]]
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[[Category: Withers SG]]

Current revision

Structure of Neisseria LOS-specific sialyltransferase (NST), in complex with CMP-3F-Neu5Ac.

PDB ID 2yk7

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