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4a15

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Current revision (11:17, 20 December 2023) (edit) (undo)
 
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<StructureSection load='4a15' size='340' side='right'caption='[[4a15]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4a15' size='340' side='right'caption='[[4a15]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/"thermoplasma_acidophila"_(sic)_darland_et_al._1970 "thermoplasma acidophila" (sic) darland et al. 1970]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4a15]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermoplasma_acidophilum Thermoplasma acidophilum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A15 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A15 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[2vsf|2vsf]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=SF4:IRON/SULFUR+CLUSTER'>SF4</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/DNA_helicase DNA helicase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.6.4.12 3.6.4.12] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [https://pdbe.org/4a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [https://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a15 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a15 OCA], [https://pdbe.org/4a15 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a15 RCSB], [https://www.ebi.ac.uk/pdbsum/4a15 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a15 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC]] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).
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[https://www.uniprot.org/uniprot/XPD_THEAC XPD_THEAC] ATP-dependent 5'-3' DNA helicase involved in nucleotide excision repair (NER) of DNA (By similarity).
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: DNA helicase]]
 
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Kisker, C]]
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[[Category: Thermoplasma acidophilum]]
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[[Category: Kuper, J]]
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[[Category: Kisker C]]
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[[Category: Michels, G]]
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[[Category: Kuper J]]
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[[Category: Wolski, S C]]
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[[Category: Michels G]]
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[[Category: Helicase]]
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[[Category: Wolski SC]]
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[[Category: Hydrolase]]
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[[Category: Nucleotide excision repair]]
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Current revision

Crystal structure of an XPD DNA complex

PDB ID 4a15

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