This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4a3y

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:19, 20 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='4a3y' size='340' side='right'caption='[[4a3y]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
<StructureSection load='4a3y' size='340' side='right'caption='[[4a3y]], [[Resolution|resolution]] 2.15&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4a3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Ophioxylon_serpentinum Ophioxylon serpentinum]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A3Y FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4a3y]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Rauvolfia_serpentina Rauvolfia serpentina]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A3Y OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A3Y FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.15&#8491;</td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Raucaffricine_beta-glucosidase Raucaffricine beta-glucosidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.125 3.2.1.125] </span></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a3y OCA], [https://pdbe.org/4a3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a3y RCSB], [https://www.ebi.ac.uk/pdbsum/4a3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a3y ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a3y FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a3y OCA], [https://pdbe.org/4a3y PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a3y RCSB], [https://www.ebi.ac.uk/pdbsum/4a3y PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a3y ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/RG1_RAUSE RG1_RAUSE] Glucosidase specifically involved in alkaloid biosynthesis leading to the accumulation of several alkaloids, including ajmaline, an important plant-derived pharmaceutical used in the treatment of heart disorders.<ref>PMID:10975500</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 25: Line 27:
</StructureSection>
</StructureSection>
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Ophioxylon serpentinum]]
+
[[Category: Rauvolfia serpentina]]
-
[[Category: Raucaffricine beta-glucosidase]]
+
[[Category: Barleben L]]
-
[[Category: Barleben, L]]
+
[[Category: Lin H]]
-
[[Category: Lin, H]]
+
[[Category: Panjikar S]]
-
[[Category: Panjikar, S]]
+
[[Category: Rajendran C]]
-
[[Category: Rajendran, C]]
+
[[Category: Ruppert M]]
-
[[Category: Ruppert, M]]
+
[[Category: Stoeckigt J]]
-
[[Category: Stoeckigt, J]]
+
[[Category: Wang M]]
-
[[Category: Wang, M]]
+
[[Category: Xia L]]
-
[[Category: Xia, L]]
+
-
[[Category: Alkaloid]]
+
-
[[Category: Hydrolase]]
+

Current revision

Crystal structure of Raucaffricine glucosidase from ajmaline biosynthesis pathway

PDB ID 4a3y

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4a3y"
Personal tools