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4a4p

From Proteopedia

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[[Image:4a4p.jpg|left|200px]]
 
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{{STRUCTURE_4a4p| PDB=4a4p | SCENE= }}
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==crystal structure of the Sec7 domain from human cytohesin1==
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<StructureSection load='4a4p' size='340' side='right'caption='[[4a4p]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
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===crystal structure of the Sec7 domain from human cytohesin1===
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4a4p]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4P OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4A4P FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
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==About this Structure==
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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[[4a4p]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4A4P OCA].
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4a4p FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4a4p OCA], [https://pdbe.org/4a4p PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4a4p RCSB], [https://www.ebi.ac.uk/pdbsum/4a4p PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4a4p ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/CYH1_HUMAN CYH1_HUMAN] Promotes guanine-nucleotide exchange on ARF1 and ARF5. Promotes the activation of ARF factors through replacement of GDP with GTP.<ref>PMID:10652308</ref> <ref>PMID:9653114</ref>
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== References ==
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<references/>
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__TOC__
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</StructureSection>
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
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[[Category: Biou, V.]]
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[[Category: Large Structures]]
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[[Category: Cherfils, J.]]
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[[Category: Biou V]]
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[[Category: Thompson, A W.]]
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[[Category: Cherfils J]]
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[[Category: Zeeh, J C.]]
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[[Category: Thompson AW]]
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[[Category: All alpha]]
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[[Category: Zeeh JC]]
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[[Category: Guanine-nucleotide releasing factor]]
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[[Category: Signaling protein]]
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Current revision

crystal structure of the Sec7 domain from human cytohesin1

PDB ID 4a4p

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