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4aez

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==Crystal Structure of Mitotic Checkpoint Complex==
==Crystal Structure of Mitotic Checkpoint Complex==
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<StructureSection load='4aez' size='340' side='right' caption='[[4aez]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
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<StructureSection load='4aez' size='340' side='right'caption='[[4aez]], [[Resolution|resolution]] 2.30&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4aez]] is a 9 chain structure with sequence from [http://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AEZ OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AEZ FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4aez]] is a 9 chain structure with sequence from [https://en.wikipedia.org/wiki/Schizosaccharomyces_pombe Schizosaccharomyces pombe]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AEZ OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AEZ FirstGlance]. <br>
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</td></tr><tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4aez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aez OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4aez RCSB], [http://www.ebi.ac.uk/pdbsum/4aez PDBsum]</span></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.3&#8491;</td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4aez FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4aez OCA], [https://pdbe.org/4aez PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4aez RCSB], [https://www.ebi.ac.uk/pdbsum/4aez PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4aez ProSAT]</span></td></tr>
</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/SLP1_SCHPO SLP1_SCHPO] Required for mad2-dependent spindle checkpoint activation. Promotes ubiquitin-dependent degradation of cdc13 by the anaphase promoting complex/cyclosome (APC/C).<ref>PMID:15791259</ref> <ref>PMID:9001228</ref> <ref>PMID:9461438</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4aez" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[WD-repeat protein 3D structures|WD-repeat protein 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Large Structures]]
[[Category: Schizosaccharomyces pombe]]
[[Category: Schizosaccharomyces pombe]]
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[[Category: Barford, D]]
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[[Category: Barford D]]
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[[Category: Chao, W C.H]]
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[[Category: Chao WCH]]
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[[Category: Kulkarni, K A]]
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[[Category: Kulkarni KA]]
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[[Category: Zhang, Z]]
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[[Category: Zhang Z]]
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[[Category: Apc/c]]
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[[Category: Cell cycle]]
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[[Category: D-box]]
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[[Category: Ken-box]]
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Crystal Structure of Mitotic Checkpoint Complex

PDB ID 4aez

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