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4auc

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==Bovine chymosin in complex with Pepstatin A==
==Bovine chymosin in complex with Pepstatin A==
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<StructureSection load='4auc' size='340' side='right' caption='[[4auc]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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<StructureSection load='4auc' size='340' side='right'caption='[[4auc]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4auc]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomyces Actinomyces] and [http://en.wikipedia.org/wiki/Bovin Bovin]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AUC OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4AUC FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4auc]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomyces Actinomyces] and [https://en.wikipedia.org/wiki/Bos_taurus Bos taurus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AUC OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AUC FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.6&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene>, <scene name='pdbligand=STA:STATINE'>STA</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CD:CADMIUM+ION'>CD</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=IVA:ISOVALERIC+ACID'>IVA</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=STA:STATINE'>STA</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Chymosin Chymosin], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.23.4 3.4.23.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4auc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4auc OCA], [https://pdbe.org/4auc PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4auc RCSB], [https://www.ebi.ac.uk/pdbsum/4auc PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4auc ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4auc FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4auc OCA], [http://pdbe.org/4auc PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4auc RCSB], [http://www.ebi.ac.uk/pdbsum/4auc PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4auc ProSAT]</span></td></tr>
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</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN]] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.
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[https://www.uniprot.org/uniprot/CHYM_BOVIN CHYM_BOVIN] Chymosin is synthesized in the mucosa of the abomasum (fourth stomach) of young (unweaned) ruminants. The enzyme hydrolyzes casein to paracasein.
__TOC__
__TOC__
</StructureSection>
</StructureSection>
[[Category: Actinomyces]]
[[Category: Actinomyces]]
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[[Category: Bovin]]
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[[Category: Bos taurus]]
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[[Category: Chymosin]]
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[[Category: Large Structures]]
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[[Category: Brink, J M.van den]]
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[[Category: Jacobsen J]]
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[[Category: Jacobsen, J]]
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[[Category: Langholm Jensen J]]
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[[Category: Jensen, J Langholm]]
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[[Category: Larsen S]]
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[[Category: Larsen, S]]
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[[Category: Navarro Poulsen JC]]
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[[Category: Poulsen, J C.Navarro]]
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[[Category: Qvist KB]]
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[[Category: Qvist, K B]]
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[[Category: Van den Brink JM]]
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[[Category: Hydrolase]]
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[[Category: Hydrolase inhibitor]]
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[[Category: Hydrolase-hydrolase inhibitor complex]]
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[[Category: Inhibition]]
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[[Category: Peptidase]]
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Current revision

Bovine chymosin in complex with Pepstatin A

PDB ID 4auc

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