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4ayu

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Current revision (11:39, 20 December 2023) (edit) (undo)
 
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== Structural highlights ==
== Structural highlights ==
<table><tr><td colspan='2'>[[4ayu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AYU FirstGlance]. <br>
<table><tr><td colspan='2'>[[4ayu]] is a 5 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4AYU OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4AYU FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=N8P:N-ACETYL-D-PROLINE'>N8P</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1gyk|1gyk]], [[1lgn|1lgn]], [[1sac|1sac]], [[2a3w|2a3w]], [[2a3x|2a3x]], [[2a3y|2a3y]], [[2w08|2w08]], [[4avs|4avs]], [[4avt|4avt]], [[4avv|4avv]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CA:CALCIUM+ION'>CA</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene>, <scene name='pdbligand=N8P:N-ACETYL-D-PROLINE'>N8P</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ayu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ayu OCA], [https://pdbe.org/4ayu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ayu RCSB], [https://www.ebi.ac.uk/pdbsum/4ayu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ayu ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4ayu FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4ayu OCA], [https://pdbe.org/4ayu PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4ayu RCSB], [https://www.ebi.ac.uk/pdbsum/4ayu PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4ayu ProSAT]</span></td></tr>
</table>
</table>
== Disease ==
== Disease ==
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[[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
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[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN] Note=SAP is a precursor of amyloid component P which is found in basement membrane and associated with amyloid deposits.
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN]] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
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[https://www.uniprot.org/uniprot/SAMP_HUMAN SAMP_HUMAN] Can interact with DNA and histones and may scavenge nuclear material released from damaged circulating cells. May also function as a calcium-dependent lectin.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Hughes, P]]
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[[Category: Hughes P]]
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[[Category: Kolstoe, S E]]
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[[Category: Kolstoe SE]]
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[[Category: Wood, S P]]
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[[Category: Wood SP]]
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[[Category: Lectin]]
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[[Category: Sugar binding protein]]
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Current revision

Structure of N-Acetyl-D-Proline bound to serum amyloid P component

PDB ID 4ayu

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