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4b14
From Proteopedia
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==Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 26)== | ==Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 26)== | ||
| - | <StructureSection load='4b14' size='340' side='right' caption='[[4b14]], [[Resolution|resolution]] 1.50Å' scene=''> | + | <StructureSection load='4b14' size='340' side='right'caption='[[4b14]], [[Resolution|resolution]] 1.50Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4b14]] is a 3 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4b14]] is a 3 chain structure with sequence from [https://en.wikipedia.org/wiki/Plasmodium_vivax Plasmodium vivax]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B14 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B14 FirstGlance]. <br> |
| - | </td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=4XB:3-METHOXYBENZYL+3-METHYL-4-(PIPERIDIN-4-YLOXY)-1-BENZOFURAN-2-CARBOXYLATE'>4XB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NHW:2-OXOPENTADECYL-COA'>NHW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.5Å</td></tr> |
| - | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=4XB:3-METHOXYBENZYL+3-METHYL-4-(PIPERIDIN-4-YLOXY)-1-BENZOFURAN-2-CARBOXYLATE'>4XB</scene>, <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=DMS:DIMETHYL+SULFOXIDE'>DMS</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NHW:2-OXOPENTADECYL-COA'>NHW</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> | |
| - | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b14 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b14 OCA], [https://pdbe.org/4b14 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b14 RCSB], [https://www.ebi.ac.uk/pdbsum/4b14 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b14 ProSAT]</span></td></tr> | |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
| + | == Function == | ||
| + | [https://www.uniprot.org/uniprot/A5K1A2_PLAVS A5K1A2_PLAVS] Adds a myristoyl group to the N-terminal glycine residue of certain cellular proteins (By similarity).[RuleBase:RU000586] | ||
<div style="background-color:#fffaf0;"> | <div style="background-color:#fffaf0;"> | ||
== Publication Abstract from PubMed == | == Publication Abstract from PubMed == | ||
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From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | From MEDLINE®/PubMed®, a database of the U.S. National Library of Medicine.<br> | ||
</div> | </div> | ||
| + | <div class="pdbe-citations 4b14" style="background-color:#fffaf0;"></div> | ||
== References == | == References == | ||
<references/> | <references/> | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Large Structures]] |
[[Category: Plasmodium vivax]] | [[Category: Plasmodium vivax]] | ||
| - | [[Category: Brannigan | + | [[Category: Brannigan JA]] |
| - | [[Category: Brzozowski | + | [[Category: Brzozowski AM]] |
| - | [[Category: Holder | + | [[Category: Holder AA]] |
| - | [[Category: Leatherbarrow | + | [[Category: Leatherbarrow RJ]] |
| - | [[Category: Moss | + | [[Category: Moss DK]] |
| - | [[Category: Tate | + | [[Category: Tate EW]] |
| - | [[Category: Wilkinson | + | [[Category: Wilkinson AJ]] |
| - | [[Category: Yu | + | [[Category: Yu Z]] |
| - | + | ||
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Current revision
Plasmodium vivax N-myristoyltransferase with a bound benzofuran inhibitor (compound 26)
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