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4b44

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==Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH6.5==
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<StructureSection load='4b44' size='340' side='right' caption='[[4b44]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
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==Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH8.0==
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<StructureSection load='4b44' size='340' side='right'caption='[[4b44]], [[Resolution|resolution]] 2.70&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b44]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermus_thermophilus_hb8 Thermus thermophilus hb8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B44 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b44]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermus_thermophilus_HB8 Thermus thermophilus HB8]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B44 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B44 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.7&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b3x|4b3x]], [[4b43|4b43]], [[4b47|4b47]], [[4b48|4b48]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=GDP:GUANOSINE-5-DIPHOSPHATE'>GDP</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b44 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b44 RCSB], [http://www.ebi.ac.uk/pdbsum/4b44 PDBsum]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b44 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b44 OCA], [https://pdbe.org/4b44 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b44 RCSB], [https://www.ebi.ac.uk/pdbsum/4b44 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b44 ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[http://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8]] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
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[https://www.uniprot.org/uniprot/IF2_THET8 IF2_THET8] One of the essential components for the initiation of protein synthesis. Protects formylmethionyl-tRNA from spontaneous hydrolysis and promotes its binding to the 30S ribosomal subunits. Also involved in the hydrolysis of GTP during the formation of the 70S ribosomal complex (By similarity).
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Thermus thermophilus hb8]]
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[[Category: Large Structures]]
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[[Category: Klaholz, B P]]
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[[Category: Thermus thermophilus HB8]]
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[[Category: Simonetti, A]]
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[[Category: Klaholz BP]]
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[[Category: Urzhumtsev, A]]
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[[Category: Simonetti A]]
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[[Category: Gtp hydrolysis mechanism]]
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[[Category: Urzhumtsev A]]
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[[Category: Initiation]]
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[[Category: Translation]]
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Current revision

Bacterial translation initiation factor IF2 (1-363), complex with GDP at pH8.0

PDB ID 4b44

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