4b4x

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{{STRUCTURE_4b4x| PDB=4b4x | SCENE= }}
 
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===Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor===
 
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==Function==
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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor==
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[[http://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
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<StructureSection load='4b4x' size='340' side='right'caption='[[4b4x]], [[Resolution|resolution]] 2.65&Aring;' scene=''>
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== Structural highlights ==
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<table><tr><td colspan='2'>[[4b4x]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_sp._R39 Actinomadura sp. R39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4X OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4X FirstGlance]. <br>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.65&#8491;</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=HQZ:TRIHYDROXY{(1S)-1-[(METHYLSULFONYL)AMINO]ETHYL}BORATE(1-)'>HQZ</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4x OCA], [https://pdbe.org/4b4x PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4x RCSB], [https://www.ebi.ac.uk/pdbsum/4b4x PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4x ProSAT]</span></td></tr>
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</table>
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== Function ==
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[https://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
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==About this Structure==
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==See Also==
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[[4b4x]] is a 4 chain structure with sequence from [http://en.wikipedia.org/wiki/Actinomadura_sp_r39 Actinomadura sp r39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4X OCA].
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*[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]]
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[[Category: Actinomadura sp r39]]
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*[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]]
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[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
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__TOC__
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[[Category: Cannella, S E.]]
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</StructureSection>
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[[Category: Charlier, P.]]
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[[Category: Actinomadura sp. R39]]
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[[Category: Herman, R.]]
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[[Category: Large Structures]]
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[[Category: Kerff, F.]]
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[[Category: Cannella SE]]
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[[Category: Rocaboy, M.]]
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[[Category: Charlier P]]
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[[Category: Sauvage, E.]]
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[[Category: Herman R]]
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[[Category: Hydrolase]]
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[[Category: Kerff F]]
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[[Category: Peptidoglycan]]
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[[Category: Rocaboy M]]
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[[Category: Sauvage E]]

Current revision

Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor

PDB ID 4b4x

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