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4b4z
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==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor== | ==Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor== | ||
| - | <StructureSection load='4b4z' size='340' side='right' caption='[[4b4z]], [[Resolution|resolution]] 2.20Å' scene=''> | + | <StructureSection load='4b4z' size='340' side='right'caption='[[4b4z]], [[Resolution|resolution]] 2.20Å' scene=''> |
== Structural highlights == | == Structural highlights == | ||
| - | <table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [ | + | <table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_sp._R39 Actinomadura sp. R39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4Z FirstGlance]. <br> |
| - | </td></tr><tr id=' | + | </td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2Å</td></tr> |
| - | <tr id=' | + | <tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr> |
| - | < | + | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4z OCA], [https://pdbe.org/4b4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4z RCSB], [https://www.ebi.ac.uk/pdbsum/4b4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4z ProSAT]</span></td></tr> |
| - | <tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[ | + | |
</table> | </table> | ||
== Function == | == Function == | ||
| - | [ | + | [https://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors. |
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| + | ==See Also== | ||
| + | *[[Carboxypeptidase 3D structures|Carboxypeptidase 3D structures]] | ||
| + | *[[Penicillin-binding protein 3D structures|Penicillin-binding protein 3D structures]] | ||
__TOC__ | __TOC__ | ||
</StructureSection> | </StructureSection> | ||
| - | [[Category: | + | [[Category: Actinomadura sp. R39]] |
| - | [[Category: | + | [[Category: Large Structures]] |
| - | [[Category: Cannella | + | [[Category: Cannella SE]] |
| - | [[Category: Charlier | + | [[Category: Charlier P]] |
| - | [[Category: Herman | + | [[Category: Herman R]] |
| - | [[Category: Kerff | + | [[Category: Kerff F]] |
| - | [[Category: Rocaboy | + | [[Category: Rocaboy M]] |
| - | [[Category: Sauvage | + | [[Category: Sauvage E]] |
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Current revision
Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor
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