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4b4z

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Current revision (11:43, 20 December 2023) (edit) (undo)
 
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<StructureSection load='4b4z' size='340' side='right'caption='[[4b4z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
<StructureSection load='4b4z' size='340' side='right'caption='[[4b4z]], [[Resolution|resolution]] 2.20&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_sp._r39 Actinomadura sp. r39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4Z FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b4z]] is a 4 chain structure with sequence from [https://en.wikipedia.org/wiki/Actinomadura_sp._R39 Actinomadura sp. R39]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B4Z OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B4Z FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.2&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[1w79|1w79]], [[1w8q|1w8q]], [[1w8y|1w8y]], [[2vgj|2vgj]], [[2vgk|2vgk]], [[2wke|2wke]], [[2xdm|2xdm]], [[2xk1|2xk1]], [[2xln|2xln]], [[2y4a|2y4a]], [[2y55|2y55]], [[2y59|2y59]], [[3zvt|3zvt]], [[3zvw|3zvw]], [[4b4x|4b4x]]</div></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=BSF:{[(BENZYLSULFONYL)AMINO]METHYL}BORONIC+ACID'>BSF</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Serine-type_D-Ala-D-Ala_carboxypeptidase Serine-type D-Ala-D-Ala carboxypeptidase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.16.4 3.4.16.4] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4z OCA], [https://pdbe.org/4b4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4z RCSB], [https://www.ebi.ac.uk/pdbsum/4b4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4z ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b4z FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b4z OCA], [https://pdbe.org/4b4z PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b4z RCSB], [https://www.ebi.ac.uk/pdbsum/4b4z PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b4z ProSAT]</span></td></tr>
</table>
</table>
== Function ==
== Function ==
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[[https://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP]] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
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[https://www.uniprot.org/uniprot/DAC_ACTSP DAC_ACTSP] Removes C-terminal D-alanyl residues from sugar-peptide cell wall precursors.
==See Also==
==See Also==
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__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Actinomadura sp. r39]]
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[[Category: Actinomadura sp. R39]]
[[Category: Large Structures]]
[[Category: Large Structures]]
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[[Category: Serine-type D-Ala-D-Ala carboxypeptidase]]
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[[Category: Cannella SE]]
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[[Category: Cannella, S E]]
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[[Category: Charlier P]]
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[[Category: Charlier, P]]
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[[Category: Herman R]]
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[[Category: Herman, R]]
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[[Category: Kerff F]]
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[[Category: Kerff, F]]
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[[Category: Rocaboy M]]
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[[Category: Rocaboy, M]]
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[[Category: Sauvage E]]
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[[Category: Sauvage, E]]
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[[Category: Boronic acid]]
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[[Category: Hydrolase]]
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[[Category: Peptidoglycan]]
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Current revision

Crystal structure of a complex between Actinomadura R39 DD-peptidase and a sulfonamide boronate inhibitor

PDB ID 4b4z

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