This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4b80

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:45, 20 December 2023) (edit) (undo)
 
(4 intermediate revisions not shown.)
Line 1: Line 1:
==Mus musculus Acetylcholinesterase in complex with N-(2-Diethylamino-ethyl)-1-(4-fluoro-phenyl)-methanesulfonamide==
==Mus musculus Acetylcholinesterase in complex with N-(2-Diethylamino-ethyl)-1-(4-fluoro-phenyl)-methanesulfonamide==
-
<StructureSection load='4b80' size='340' side='right' caption='[[4b80]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
+
<StructureSection load='4b80' size='340' side='right'caption='[[4b80]], [[Resolution|resolution]] 2.50&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4b80]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Lk3_transgenic_mice Lk3 transgenic mice]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B80 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B80 FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4b80]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B80 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B80 FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=A36:N-[2-(DIETHYLAMINO)ETHYL]-1-(4-FLUOROPHENYL)METHANESULFONAMIDE'>A36</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>, <scene name='pdbligand=P4C:O-ACETALDEHYDYL-HEXAETHYLENE+GLYCOL'>P4C</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.5&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[1c2b|1c2b]], [[1c2o|1c2o]], [[1j06|1j06]], [[1j07|1j07]], [[1ku6|1ku6]], [[1maa|1maa]], [[1mah|1mah]], [[1n5m|1n5m]], [[1n5r|1n5r]], [[1q83|1q83]], [[1q84|1q84]], [[2c0p|2c0p]], [[2c0q|2c0q]], [[2h9y|2h9y]], [[2ha0|2ha0]], [[2ha2|2ha2]], [[2ha3|2ha3]], [[2ha4|2ha4]], [[2ha5|2ha5]], [[2ha6|2ha6]], [[2ha7|2ha7]], [[2jey|2jey]], [[2jez|2jez]], [[2jf0|2jf0]], [[2jge|2jge]], [[2jgf|2jgf]], [[2jgg|2jgg]], [[2jgh|2jgh]], [[2jgi|2jgi]], [[2jgj|2jgj]], [[2jgk|2jgk]], [[2jgl|2jgl]], [[2jgm|2jgm]], [[2whp|2whp]], [[2whq|2whq]], [[2whr|2whr]], [[2wls|2wls]], [[2wu3|2wu3]], [[2wu4|2wu4]], [[2xud|2xud]], [[2xuf|2xuf]], [[2xug|2xug]], [[2xuh|2xuh]], [[2xui|2xui]], [[2xuj|2xuj]], [[2xuk|2xuk]], [[2xuo|2xuo]], [[2xup|2xup]], [[2xuq|2xuq]], [[4a16|4a16]], [[4a23|4a23]], [[4ara|4ara]], [[4arb|4arb]], [[4b7z|4b7z]], [[4b81|4b81]], [[4b82|4b82]], [[4b83|4b83]], [[4b84|4b84]], [[4b85|4b85]]</td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=A36:N-[2-(DIETHYLAMINO)ETHYL]-1-(4-FLUOROPHENYL)METHANESULFONAMIDE'>A36</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=P4C:O-ACETALDEHYDYL-HEXAETHYLENE+GLYCOL'>P4C</scene>, <scene name='pdbligand=PEG:DI(HYDROXYETHYL)ETHER'>PEG</scene>, <scene name='pdbligand=PGE:TRIETHYLENE+GLYCOL'>PGE</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b80 OCA], [https://pdbe.org/4b80 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b80 RCSB], [https://www.ebi.ac.uk/pdbsum/4b80 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b80 ProSAT]</span></td></tr>
-
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b80 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b80 OCA], [http://pdbe.org/4b80 PDBe], [http://www.rcsb.org/pdb/explore.do?structureId=4b80 RCSB], [http://www.ebi.ac.uk/pdbsum/4b80 PDBsum], [http://prosat.h-its.org/prosat/prosatexe?pdbcode=4b80 ProSAT]</span></td></tr>
+
</table>
</table>
== Function ==
== Function ==
-
[[http://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE]] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
+
[https://www.uniprot.org/uniprot/ACES_MOUSE ACES_MOUSE] Terminates signal transduction at the neuromuscular junction by rapid hydrolysis of the acetylcholine released into the synaptic cleft.
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 21:
==See Also==
==See Also==
-
*[[Acetylcholinesterase|Acetylcholinesterase]]
+
*[[Acetylcholinesterase 3D structures|Acetylcholinesterase 3D structures]]
-
*[[3D structures of acetylcholinesterase|3D structures of acetylcholinesterase]]
+
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Acetylcholinesterase]]
+
[[Category: Large Structures]]
-
[[Category: Lk3 transgenic mice]]
+
[[Category: Mus musculus]]
-
[[Category: Akfur, C]]
+
[[Category: Akfur C]]
-
[[Category: Allgardsson, A]]
+
[[Category: Allgardsson A]]
-
[[Category: Andersson, C D]]
+
[[Category: Andersson CD]]
-
[[Category: Berg, L]]
+
[[Category: Berg L]]
-
[[Category: Ekstrom, F]]
+
[[Category: Ekstrom F]]
-
[[Category: Forsgren, N]]
+
[[Category: Forsgren N]]
-
[[Category: Linusson, A]]
+
[[Category: Linusson A]]
-
[[Category: Qian, W]]
+
[[Category: Qian W]]
-
[[Category: Hydrolase]]
+
-
[[Category: Inhibitor]]
+

Current revision

Mus musculus Acetylcholinesterase in complex with N-(2-Diethylamino-ethyl)-1-(4-fluoro-phenyl)-methanesulfonamide

PDB ID 4b80

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4b80"
Personal tools