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4b8s

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==Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)==
==Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)==
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<StructureSection load='4b8s' size='340' side='right' caption='[[4b8s]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
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<StructureSection load='4b8s' size='340' side='right'caption='[[4b8s]], [[Resolution|resolution]] 2.58&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4b8s]] is a 1 chain structure with sequence from [http://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8S OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4B8S FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4b8s]] is a 1 chain structure with sequence from [https://en.wikipedia.org/wiki/Thermococcus_litoralis Thermococcus litoralis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4B8S OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4B8S FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2.58&#8491;</td></tr>
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<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat">[[4b8r|4b8r]]</td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=AMP:ADENOSINE+MONOPHOSPHATE'>AMP</scene>, <scene name='pdbligand=GLC:ALPHA-D-GLUCOSE'>GLC</scene>, <scene name='pdbligand=GOL:GLYCEROL'>GOL</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/ADP-specific_glucokinase ADP-specific glucokinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.1.147 2.7.1.147] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4b8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8s OCA], [https://pdbe.org/4b8s PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4b8s RCSB], [https://www.ebi.ac.uk/pdbsum/4b8s PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4b8s ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4b8s FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4b8s OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4b8s RCSB], [http://www.ebi.ac.uk/pdbsum/4b8s PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/GLKA_THELN GLKA_THELN] Catalyzes the phosphorylation of D-glucose to D-glucose 6-phosphate using ADP as the phosphate donor. Can also use CDP as the phosphoryl group donor and D-glucosamine and D-1,5-anhydroglucitol as the phosphoryl group acceptor.<ref>PMID:11098152</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4b8s" style="background-color:#fffaf0;"></div>
==See Also==
==See Also==
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*[[Hexokinase|Hexokinase]]
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*[[Hexokinase 3D structures|Hexokinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: ADP-specific glucokinase]]
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[[Category: Large Structures]]
[[Category: Thermococcus litoralis]]
[[Category: Thermococcus litoralis]]
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[[Category: Fernandez, F J]]
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[[Category: Fernandez FJ]]
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[[Category: Guixe, V]]
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[[Category: Guixe V]]
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[[Category: Herrera-Morande, A]]
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[[Category: Herrera-Morande A]]
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[[Category: Rivas-Pardo, J A]]
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[[Category: Rivas-Pardo JA]]
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[[Category: Vega, M C]]
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[[Category: Vega MC]]
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[[Category: Ribokinase superfamily]]
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[[Category: Transferase]]
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Current revision

Crystal Structure of Thermococcus litoralis ADP-dependent Glucokinase (GK)

PDB ID 4b8s

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