This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


4bbm

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Current revision (11:47, 20 December 2023) (edit) (undo)
 
Line 3: Line 3:
<StructureSection load='4bbm' size='340' side='right'caption='[[4bbm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
<StructureSection load='4bbm' size='340' side='right'caption='[[4bbm]], [[Resolution|resolution]] 2.00&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
-
<table><tr><td colspan='2'>[[4bbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Human Human]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BBM FirstGlance]. <br>
+
<table><tr><td colspan='2'>[[4bbm]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BBM OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BBM FirstGlance]. <br>
-
</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TC0:4-[5-[[3-[(CYCLOPROPYLAMINO)METHYL]PHENYL]AMINO]-1H-PYRAZOL-3-YL]-[1,1-BIPHENYL]-2,4-DIOL'>TC0</scene></td></tr>
+
</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 2&#8491;</td></tr>
-
<tr id='related'><td class="sblockLbl"><b>[[Related_structure|Related:]]</b></td><td class="sblockDat"><div style='overflow: auto; max-height: 3em;'>[[4aaa|4aaa]]</div></td></tr>
+
<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=EDO:1,2-ETHANEDIOL'>EDO</scene>, <scene name='pdbligand=TC0:4-[5-[[3-[(CYCLOPROPYLAMINO)METHYL]PHENYL]AMINO]-1H-PYRAZOL-3-YL]-[1,1-BIPHENYL]-2,4-DIOL'>TC0</scene></td></tr>
-
<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[https://en.wikipedia.org/wiki/Cyclin-dependent_kinase Cyclin-dependent kinase], with EC number [https://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.11.22 2.7.11.22] </span></td></tr>
+
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bbm OCA], [https://pdbe.org/4bbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bbm RCSB], [https://www.ebi.ac.uk/pdbsum/4bbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bbm ProSAT]</span></td></tr>
<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bbm FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bbm OCA], [https://pdbe.org/4bbm PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bbm RCSB], [https://www.ebi.ac.uk/pdbsum/4bbm PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bbm ProSAT]</span></td></tr>
</table>
</table>
 +
== Function ==
 +
[https://www.uniprot.org/uniprot/CDKL2_HUMAN CDKL2_HUMAN]
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
Line 22: Line 23:
__TOC__
__TOC__
</StructureSection>
</StructureSection>
-
[[Category: Cyclin-dependent kinase]]
+
[[Category: Homo sapiens]]
-
[[Category: Human]]
+
[[Category: Large Structures]]
[[Category: Large Structures]]
-
[[Category: Arrowsmith, C H]]
+
[[Category: Arrowsmith CH]]
-
[[Category: Berridge, G]]
+
[[Category: Berridge G]]
-
[[Category: Bountra, C]]
+
[[Category: Bountra C]]
-
[[Category: Bullock, A]]
+
[[Category: Bullock A]]
-
[[Category: Burgess-Brown, N]]
+
[[Category: Burgess-Brown N]]
-
[[Category: Canning, P]]
+
[[Category: Canning P]]
-
[[Category: Cooper, C D.O]]
+
[[Category: Cooper CDO]]
-
[[Category: Daga, N]]
+
[[Category: Daga N]]
-
[[Category: Delft, F von]]
+
[[Category: Edwards AM]]
-
[[Category: Edwards, A M]]
+
[[Category: Elkins JM]]
-
[[Category: Elkins, J M]]
+
[[Category: Krojer T]]
-
[[Category: Krojer, T]]
+
[[Category: Mahajan P]]
-
[[Category: Mahajan, P]]
+
[[Category: Muniz JRC]]
-
[[Category: Muniz, J R.C]]
+
[[Category: Von Delft F]]
-
[[Category: Phospho-mimetic]]
+
-
[[Category: Transferase]]
+

Current revision

CRYSTAL STRUCTURE OF THE HUMAN CDKL2 KINASE DOMAIN WITH BOUND TCS 2312

PDB ID 4bbm

Drag the structure with the mouse to rotate

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/4bbm"
Personal tools