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4bg4

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==Crystal structure of Litopenaeus vannamei arginine kinase in a ternary analog complex with arginine, ADP-Mg and NO_3==
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<StructureSection load='4bg4' size='340' side='right' caption='[[4bg4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
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==Crystal structure of Litopenaeus vannamei arginine kinase in a ternary analog complex with arginine, ADP-Mg and NO3==
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<StructureSection load='4bg4' size='340' side='right'caption='[[4bg4]], [[Resolution|resolution]] 1.60&Aring;' scene=''>
== Structural highlights ==
== Structural highlights ==
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<table><tr><td colspan='2'>[[4bg4]] is a 2 chain structure with sequence from [http://en.wikipedia.org/wiki/Litopenaeus_vannamei Litopenaeus vannamei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BG4 OCA]. For a <b>guided tour on the structure components</b> use [http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4BG4 FirstGlance]. <br>
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<table><tr><td colspan='2'>[[4bg4]] is a 2 chain structure with sequence from [https://en.wikipedia.org/wiki/Penaeus_vannamei Penaeus vannamei]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=4BG4 OCA]. For a <b>guided tour on the structure components</b> use [https://proteopedia.org/fgij/fg.htm?mol=4BG4 FirstGlance]. <br>
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</td></tr><tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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</td></tr><tr id='method'><td class="sblockLbl"><b>[[Empirical_models|Method:]]</b></td><td class="sblockDat" id="methodDat">X-ray diffraction, [[Resolution|Resolution]] 1.601&#8491;</td></tr>
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<tr id='NonStdRes'><td class="sblockLbl"><b>[[Non-Standard_Residue|NonStd Res:]]</b></td><td class="sblockDat"><scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene></td></tr>
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<tr id='ligand'><td class="sblockLbl"><b>[[Ligand|Ligands:]]</b></td><td class="sblockDat" id="ligandDat"><scene name='pdbligand=ADP:ADENOSINE-5-DIPHOSPHATE'>ADP</scene>, <scene name='pdbligand=ARG:ARGININE'>ARG</scene>, <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=CSO:S-HYDROXYCYSTEINE'>CSO</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NO3:NITRATE+ION'>NO3</scene></td></tr>
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<tr id='activity'><td class="sblockLbl"><b>Activity:</b></td><td class="sblockDat"><span class='plainlinks'>[http://en.wikipedia.org/wiki/Arginine_kinase Arginine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.3.3 2.7.3.3] </span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[https://proteopedia.org/fgij/fg.htm?mol=4bg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bg4 OCA], [https://pdbe.org/4bg4 PDBe], [https://www.rcsb.org/pdb/explore.do?structureId=4bg4 RCSB], [https://www.ebi.ac.uk/pdbsum/4bg4 PDBsum], [https://prosat.h-its.org/prosat/prosatexe?pdbcode=4bg4 ProSAT]</span></td></tr>
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<tr id='resources'><td class="sblockLbl"><b>Resources:</b></td><td class="sblockDat"><span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=4bg4 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=4bg4 OCA], [http://www.rcsb.org/pdb/explore.do?structureId=4bg4 RCSB], [http://www.ebi.ac.uk/pdbsum/4bg4 PDBsum]</span></td></tr>
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</table>
</table>
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== Function ==
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[https://www.uniprot.org/uniprot/KARG0_PENVA KARG0_PENVA] Catalyzes the reversible transfer of high energy ATP gamma-phosphate group to L-arginine (PubMed:17496423, PubMed:27072556, PubMed:22750864, PubMed:23873077). Has nucleoside diphosphate kinase-like activity toward dTDP. Binds and phosphorylates dTDP using ATP as a phosphate donor. Does not phosphorylate dADP, dCDP, dGDP, dTMP or thymidine (PubMed:27072556).<ref>PMID:17496423</ref> <ref>PMID:22750864</ref> <ref>PMID:23873077</ref> <ref>PMID:27072556</ref>
<div style="background-color:#fffaf0;">
<div style="background-color:#fffaf0;">
== Publication Abstract from PubMed ==
== Publication Abstract from PubMed ==
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From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
From MEDLINE&reg;/PubMed&reg;, a database of the U.S. National Library of Medicine.<br>
</div>
</div>
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<div class="pdbe-citations 4bg4" style="background-color:#fffaf0;"></div>
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==See Also==
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*[[Arginine kinase 3D structures|Arginine kinase 3D structures]]
== References ==
== References ==
<references/>
<references/>
__TOC__
__TOC__
</StructureSection>
</StructureSection>
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[[Category: Arginine kinase]]
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[[Category: Large Structures]]
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[[Category: Litopenaeus vannamei]]
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[[Category: Penaeus vannamei]]
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[[Category: Carrasco-Miranda, J S]]
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[[Category: Carrasco-Miranda JS]]
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[[Category: Criscitiello, M F]]
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[[Category: Criscitiello MF]]
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[[Category: GBrieba, L]]
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[[Category: GBrieba L]]
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[[Category: Garcia-Orozco, K D]]
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[[Category: Garcia-Orozco KD]]
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[[Category: Lopez-Zavala, A A]]
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[[Category: Lopez-Zavala AA]]
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[[Category: Rudino-Pinera, E]]
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[[Category: Rudino-Pinera E]]
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[[Category: Sotelo-Mundo, R R]]
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[[Category: Sotelo-Mundo RR]]
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[[Category: Sugich-Miranda, R]]
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[[Category: Sugich-Miranda R]]
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[[Category: Velazquez-Contreras, E F]]
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[[Category: Velazquez-Contreras EF]]
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[[Category: Binary complex]]
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[[Category: Transferase]]
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Current revision

Crystal structure of Litopenaeus vannamei arginine kinase in a ternary analog complex with arginine, ADP-Mg and NO3

PDB ID 4bg4

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